Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | SUV39H2 | Q9H5I1 | 12/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15231047 | 0.97 | RAB9A (0.58) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL15231082 | 0.96 | RAB9A (0.57) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| SCHEMBL16782277 | 0.94 | RAB9A (0.54) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| Hypochlorous Acid SCHEMBL21485982 | 0.89 | NPC1 (0.44) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| Hypochlorous Acid SCHEMBL21486121 | 0.87 | ALDH1A1 (0.55) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| SCHEMBL15230425 | 0.87 | RAB9A (0.56) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| SCHEMBL16782184 | 0.86 | NPC1 (0.46) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| SCHEMBL16782223 | 0.86 | RAB9A (0.53) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| Hydrochloric Acid SCHEMBL15230386 | 0.85 | NPC1 (0.46) | RAB9ANPC1ALDH1A1MAPTPOLB | |
| Hypochlorous Acid SCHEMBL21486160 | 0.85 | RAB9A (0.56) | RAB9ANPC1ALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2819519-B1 | COMPOUNDS FOR TREATING SPINAL MUSCULAR ATROPHY | PTC THERAPEUTICS INC (US) | 2019-10-23 | — | — | EP | claimed |