Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | CARM1 | Q86X55 | 5/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NPY2R | P49146 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.41 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3289933 | 0.94 | HRH1 (0.57) | HRH1CARM1PRMT1KDM4ESMN1; SMN2 | |
| SCHEMBL3287623 | 0.92 | MEN1 (0.46) | HRH1CARM1PRMT1NCF1MEN1 | |
| SCHEMBL23004969 | 0.83 | CARM1 (0.55) | HRH1CARM1PRMT1 | |
| SCHEMBL29786357 | 0.83 | CARM1 (0.58) | HRH1CARM1PRMT1 | |
| SCHEMBL6492804 | 0.83 | CARM1 (0.58) | HRH1CARM1PRMT1 | |
| SCHEMBL20472407 | 0.82 | CARM1 (0.61) | HRH1CARM1PRMT1 | |
| SCHEMBL29786600 | 0.82 | CARM1 (0.61) | HRH1CARM1PRMT1 | |
| SCHEMBL14624279 | 0.81 | HRH1 (0.62) | HRH1CARM1PRMT1KDM4ESMN1; SMN2 | |
| SCHEMBL23761234 | 0.80 | CARM1 (0.50) | HRH1CARM1PRMT1 | |
| SCHEMBL30856498 | 0.80 | CARM1 (0.50) | HRH1CARM1PRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197549-A1 | PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITOR OF CYCLIN DEPENDENT KINASE | QURIENT CO., LTD. (KR) | 2019-10-17 | — | — | WO | disclosed |