Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 13/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 10/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | CLK3 | P49761 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26973963 | 0.87 | CDK2 (0.37) | HRH3HRH4CDK2GSK3BCDK9 | |
| SCHEMBL21481495 | 0.82 | CDK2 (0.36) | CDK2GSK3BCDK9CCNT1CDK5 | |
| SCHEMBL23352055 | 0.79 | CDK2 (0.33) | CDK2GSK3BCDK9CCNT1CDK5 | |
| SCHEMBL15224899 | 0.77 | KDM4E (0.42) | CDK2CDK9CCNT1CDK5CDK5R1 | |
| SCHEMBL21481497 | 0.77 | CDK2 (0.33) | CDK2GSK3BCDK9CCNT1CDK5 | |
| SCHEMBL15224900 | 0.77 | KDM4E (0.42) | CDK2CDK9CCNT1CDK5CDK5R1 | |
| SCHEMBL30716366 | 0.77 | DKK1 (0.37) | HRH3HRH4CDK2GSK3BCDK9 | |
| SCHEMBL26973961 | 0.75 | ALDH1A1 (0.40) | CDK2CDK9CCNE1 | |
| SCHEMBL21481496 | 0.75 | CDK2 (0.32) | CDK2GSK3BCDK9CCNE1CDK7 | |
| SCHEMBL23381696 | 0.75 | CDK2 (0.47) | CDK2CDK9CCNT1CDK5CDK5R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019197549-A1 | PYRAZOLO-TRIAZINE AND/OR PYRAZOLO-PYRIMIDINE DERIVATIVES AS SELECTIVE INHIBITOR OF CYCLIN DEPENDENT KINASE | QURIENT CO., LTD. (KR) | 2019-10-17 | — | — | WO | disclosed |