Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.58 |
| ▸ | MC4R | P32245 | 8/20 | 0.58 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445460 | 0.83 | MC1R (0.71) | MC1RMC4RAPPGRIN2BKMT2A | |
| Trifluoroacetic Acid SCHEMBL1309977 | 0.82 | MC1R (0.56) | MC1RMC4RAPP | |
| SCHEMBL2149249 | 0.80 | MC1R (0.49) | MC1RMC4RAPPADRB1HTR2A | |
| SCHEMBL1310043 | 0.80 | MC1R (0.55) | MC1RMC4RAPPL3MBTL1GRIN2B | |
| Hydrochloric Acid SCHEMBL1310496 | 0.79 | MC1R (0.60) | MC1RMC4RAPP | |
| Hydrochloric Acid SCHEMBL1310494 | 0.79 | MC1R (0.60) | MC1RMC4RAPP | |
| SCHEMBL1309979 | 0.78 | MC1R (0.50) | MC1RMC4RAPPGRIN2B | |
| SCHEMBL2149032 | 0.78 | MC1R (0.62) | MC1RMC4RAPPL3MBTL1GRIN2B | |
| SCHEMBL16188227 | 0.76 | MC1R (0.72) | MC1RMC4RKMT2A | |
| SCHEMBL2149320 | 0.76 | MC1R (0.51) | MC1RMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |