Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.62 |
| ▸ | MC4R | P32245 | 8/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445351 | 0.85 | MC1R (0.73) | MC1RMC4RAPPGAAMAPT | |
| Trifluoroacetic Acid SCHEMBL1311384 | 0.83 | MC1R (0.58) | MC1RMC4RPOLBOPRM1OPRD1 | |
| SCHEMBL1311665 | 0.81 | MC1R (0.58) | MC1RMC4RAPPGAAMAPT | |
| SCHEMBL2149100 | 0.79 | MC1R (0.50) | MC1RMC4RAPPGAAMAPT | |
| SCHEMBL2148946 | 0.78 | MC1R (0.58) | MC1RMC4RAPPKMT2AL3MBTL1 | |
| SCHEMBL20450385 | 0.77 | MC1R (1.00) | MC1RMC4R | |
| Hydrochloric Acid SCHEMBL1310494 | 0.76 | MC1R (0.60) | MC1RMC4RAPP | |
| SCHEMBL2149249 | 0.76 | MC1R (0.49) | MC1RMC4RAPPMEN1KMT2A | |
| SCHEMBL1311385 | 0.75 | MC1R (0.49) | MC1RMC4RAPPMEN1KMT2A | |
| SCHEMBL20450443 | 0.74 | MC1R (0.51) | MC1RMC4ROPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |