Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.49 |
| ▸ | MC4R | P32245 | 8/20 | 0.49 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148946 | 0.80 | MC1R (0.58) | MC1RMC4RAPPADRB1HTR2A | |
| Hydrochloric Acid SCHEMBL1310494 | 0.76 | MC1R (0.60) | MC1RMC4RAPP | |
| Hydrochloric Acid SCHEMBL1310496 | 0.76 | MC1R (0.60) | MC1RMC4RAPP | |
| SCHEMBL2149032 | 0.76 | MC1R (0.62) | MC1RMC4RAPPGRIN2BL3MBTL1 | |
| SCHEMBL2148833 | 0.75 | MC1R (0.47) | MC1RMC4RAPPGRIN2BL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1310217 | 0.74 | MC1R (0.57) | MC1RMC4R | |
| SCHEMBL1309979 | 0.74 | MC1R (0.50) | MC1RMC4RAPPGRIN2B | |
| SCHEMBL3731642 | 0.74 | MC1R (0.47) | MC1RMC4RAPPGRIN2BMEN1 | |
| SCHEMBL2148877 | 0.73 | MC1R (0.43) | MC1RMC4RAPPGRIN2BL3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL1309977 | 0.73 | MC1R (0.56) | MC1RMC4RAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |