Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC1R | Q01726 | 8/20 | 0.57 |
| ▸ | MC4R | P32245 | 7/20 | 0.57 |
| ▸ | HRH2 | P25021 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | PTPRA | P18433 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16445371 | 0.89 | MC1R (0.62) | MC1RMC4RKMT2A | |
| Trifluoroacetic Acid SCHEMBL1310165 | 0.82 | MC1R (0.49) | MC1RMC4RHDAC8 | |
| SCHEMBL1310104 | 0.81 | MC1R (0.69) | MC1RMC4RKMT2AHDAC8 | |
| SCHEMBL20450446 | 0.81 | MC1R (0.69) | MC1RMC4RKMT2AHDAC8 | |
| SCHEMBL16188227 | 0.81 | MC1R (0.72) | MC1RMC4RKMT2A | |
| SCHEMBL1310666 | 0.80 | MC1R (0.47) | MC1RMC4RKMT2A | |
| SCHEMBL16444996 | 0.79 | MC1R (0.70) | MC1RMC4RKMT2A | |
| SCHEMBL2149298 | 0.79 | MC1R (0.53) | MC1RMC4RHRH2HRH1ALDH1A1 | |
| SCHEMBL2149537 | 0.77 | KMT2A (0.46) | MC1RMC4RHRH2HRH1ALDH1A1 | |
| SCHEMBL1312669 | 0.77 | GPR119 (0.39) | MC1RMC4RHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |