SCHEMBL214909

SCHEMBL214909

O=C(O)c1cc2cccc(O)c2cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 1.00
GRIN2A Q12879 1/20 1.00
GRIN2B Q13224 1/20 1.00
GRIN2C Q14957 1/20 1.00
KDM4E B2RXH2 5/20 0.55
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CASP1 P29466 2/20 0.55
CASP7 P55210 2/20 0.55
POLB P06746 2/20 0.55
HSD17B10 Q99714 2/20 0.55
USP2 O75604 1/20 0.55
MAOA P21397 1/20 0.53
SMYD3 Q9H7B4 2/20 0.51
MPL P40238 1/20 0.51
POLA1 P09884 1/20 0.51
ALDH1A1 P00352 3/20 0.51
CYP1A2 P05177 1/20 0.51
CYP2D6 P10635 1/20 0.51
CYP2C9 P11712 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29620342 1.00 GRIN2D (1.00) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL3391564 0.92 GRIN2D (0.86) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL10353592 0.90 GRIN2D (0.82) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL10824259 0.85 GRIN2D (0.73) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL14381082 0.84 GRIN2D (0.72) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL19820038 0.83 GRIN2D (0.71) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL9324678 0.83 GRIN2D (0.71) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
Coumaric Acid SCHEMBL7823431 0.82 GRIN2D (0.67) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL8462722 0.81 GRIN2D (0.68) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E
SCHEMBL8462678 0.81 GRIN2D (0.68) GRIN2DGRIN2AGRIN2BGRIN2CKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 716 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12163968-B2 Preparation of nucleated RBC (NRBC) analogs for use as reference hematology controls in automated hematology analyzers BIO-RAD LABORATORIES, INC. (US) 2024-12-10 US claimed
CN-118184679-A Photothermal agent and preparation method thereof, photothermal nanoparticle and preparation method thereof, insulating material and self-repairing method of insulating material 中国石油天然气股份有限公司 2024-06-14 CN claimed
CN-117416983-A Naphthoxyhc acid and/or its derivative acid radical intercalation hydrotalcite-like compound and its preparation method 中国科学院青海盐湖研究所 2024-01-19 CN claimed
CN-116836081-A Ether epoxy toughening agent and preparation method and application thereof 中国林业科学研究院林产化学工业研究所 2023-10-03 CN claimed
CN-115109833-A Quick detect reagent box of vaginitis 中山市德诺西信息科技有限公司 2022-09-27 CN claimed
US-10191398-B2 Electrophotographic photoconductor, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2019-01-29 US claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
CN-104911245-B A kind of kit for bacterial vaginosis BV detection 深圳市艾瑞生物科技有限公司 2017-11-17 CN claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
US-20040261198-A1 Restructuring and finishing of keratin fibers HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 2004-12-30 US claimed
US-20040256599-A1 Thermotorpic liquid-crystal polymer UENO FINE CHEMICALS INDUSTRY, LTD. (JP) 2004-12-23 US claimed
CN-1541237-A Thermotropic liquid-crystal polymer ��ʽ������Ұ��ҩӦ���о��� 2004-10-27 CN claimed
EP-1422256-A1 THERMOTROPIC LIQUID-CRYSTAL POLYMER Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 2004-05-26 EP claimed
US-20030212239-A1 Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings DEGUSSA AG (DE) 2003-11-13 US claimed
US-6562482-B1 Liquid potting composition SUMITOMO BAKELITE COMPANY, LTD. (JP) 2003-05-13 US claimed
US-20030044877-A1 Novel enzymatic substrates for detecting pseudomonas aeruginosa, compositions containing same and method for detecting said species BIOMERIEUX S.A. (FR) 2003-03-06 US claimed
EP-1074571-A2 Liquid potting composition SUMITOMO BAKELITE CO., LTD. (JP) 2001-02-07 EP claimed
US-4920198-A Branched polycarbonate from hydroxy-naphthoic acid or derivative, and process for preparing ENICHEM TECNORESINE S.P.A. (IT) 1990-04-24 US claimed
EP-0295737-A2 Branched polycarbonates containing hydroxy-naphthoic acids or their derivatives, and process for preparing them ENICHEM S.p.A. (IT) 1988-12-21 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS GRIN2D 4724/4885GRIN2A 4576/4885GRIN2B 4700/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS GRIN2D 4724/4885GRIN2A 4576/4885GRIN2B 4700/4885
US-20030044877-A1 Novel enzymatic substrates for detecting pseudomonas aeruginosa, compositions containing same and method for detecting said species PEPD, ENPEP, ANPEP GRIN2D 4858/4885GRIN2A 4791/4885GRIN2B 4678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.