SCHEMBL21492932

SCHEMBL21492932

CCCCNCC(=O)O.NCCCCCCNCC(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.58
MAOB P27338 1/20 0.58
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
KMT2A Q03164 2/20 0.47
ALOX15 P16050 2/20 0.47
PLG P00747 1/20 0.47
LMNA P02545 1/20 0.47
THRB P10828 1/20 0.47
SLC6A2 P23975 1/20 0.47
RECQL P46063 1/20 0.47
SLC6A3 Q01959 1/20 0.47
SLC6A5 Q9Y345 2/20 0.46
PAOX Q6QHF9 3/20 0.46
EPHX2 P34913 1/20 0.45
GNAI3 P08754 1/20 0.45
GNAO1 P09471 1/20 0.45
GNAI1 P63096 1/20 0.45
CYP2D6 P10635 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dodecylamine SCHEMBL7193288 0.96 MAOA (0.58) MAOAMAOBMEN1ALDH1A1KMT2A
SCHEMBL288829 0.90 MAOA (0.69) MAOAMAOBMEN1ALDH1A1KMT2A
SCHEMBL181523 0.90 MAOA (0.69) MAOAMAOBMEN1ALDH1A1KMT2A
Dodecylamine SCHEMBL4799042 0.89 MAOA (0.48) MAOAMAOBMEN1ALDH1A1KMT2A
SCHEMBL7700013 0.88 MAOA (0.67) MAOAMAOBMEN1ALDH1A1KMT2A
SCHEMBL163406 0.88 MAOA (0.65) MAOAMAOBMEN1ALDH1A1KMT2A
SCHEMBL25177394 0.86 GPR84 (0.56) MEN1ALDH1A1KMT2AALOX15EPHX2
SCHEMBL25211905 0.86 GPR84 (0.56) MEN1ALDH1A1KMT2AALOX15EPHX2
SCHEMBL20820026 0.86 GPR84 (0.56) MEN1ALDH1A1KMT2AALOX15EPHX2
SCHEMBL25184994 0.86 GPR84 (0.56) MEN1ALDH1A1KMT2AALOX15EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11186622-B2 PAC1 receptor agonists (MAXCAPS) and uses thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-11-30 US disclosed
US-20190322718-A1 PAC1 RECEPTOR AGONISTS (MAXCAPS) AND USES THEREOF THE UNITED STATES GOVERNMENT REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS 2019-10-24 US disclosed