SCHEMBL21493643

SCHEMBL21493643

NCCC(=O)N1C(=O)NC2C(CCCCC(=O)O)SCC21

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.52
ABL1 P00519 2/20 0.52
IDE P14735 2/20 0.52
RIN1 Q13671 2/20 0.52
MEN1 O00255 1/20 0.52
LMNA P02545 1/20 0.52
PKM P14618 1/20 0.52
MAPK1 P28482 1/20 0.52
KMT2A Q03164 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CA12 O43570 8/20 0.35
CA1 P00915 8/20 0.35
CA2 P00918 8/20 0.35
CA9 Q16790 8/20 0.35
HLCS P50747 2/20 0.34
PPARG P37231 1/20 0.33
NR2E3 Q9Y5X4 1/20 0.33
NCOR2 Q9Y618 1/20 0.33
SLC18A3 Q16572 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3423752 0.86 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL30107625 0.84 TDP1 (0.74) TDP1ABL1IDERIN1MEN1
SCHEMBL7169914 0.84 TDP1 (0.50) TDP1ABL1IDERIN1MEN1
SCHEMBL18386701 0.81 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL14617993 0.81 TDP1 (0.47) TDP1ABL1IDERIN1MEN1
SCHEMBL31297012 0.81 TDP1 (0.52) TDP1ABL1IDERIN1MEN1
SCHEMBL19751635 0.79 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL4967996 0.79 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL19751767 0.79 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL12642068 0.78 TDP1 (0.56) TDP1ABL1IDERIN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2026-05-21 US disclosed
EP-3562841-B1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF HOFFMANN LA ROCHE (CH) 2026-03-25 EP disclosed
US-12559573-B2 Biotin-specific monoclonal antibody and use thereof ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2026-02-24 US disclosed
EP-4685490-A2 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF F. Hoffmann-La Roche AG (CH) 2026-01-28 EP disclosed
EP-4653868-A2 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF F. Hoffmann-La Roche AG (CH) 2025-11-26 EP disclosed
EP-4647769-A2 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF F. Hoffmann-La Roche AG (CH) 2025-11-12 EP disclosed
US-20250306016-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS INC (US) 2025-10-02 US disclosed
EP-3562842-B1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF HOFFMANN LA ROCHE (CH) 2025-10-01 EP disclosed
EP-3562845-B1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF HOFFMANN LA ROCHE (CH) 2025-10-01 EP disclosed
US-12360108-B2 Biotin-specific monoclonal antibody and use thereof ROCHE DIAGNOSTICS OPERATIONS, INC. 2025-07-15 US disclosed
US-20240377388-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. 2024-11-14 US disclosed
US-12025613-B2 Biotin-specific monoclonal antibody and use thereof ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2024-07-02 US disclosed
US-20220106408-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS GMBH (DE) 2022-04-07 US disclosed
US-20220107310-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. 2022-04-07 US disclosed
US-20220107309-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS GMBH (DE) 2022-04-07 US disclosed
US-20190324024-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2019-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190324024-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-20220106408-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-20220107310-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-20250306016-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-12025613-B2 Biotin-specific monoclonal antibody and use thereof BTD, IGLV6-57, VIM TDP1 4556/4885ABL1 1338/4885IDE 522/4885
US-20220107309-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-12559573-B2 Biotin-specific monoclonal antibody and use thereof IGLV6-57, LY96, BTD TDP1 4725/4885ABL1 1952/4885IDE 1884/4885
US-20260139075-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF CD22, LY96, F13B TDP1 4799/4885ABL1 2440/4885IDE 1707/4885
US-20240377388-A1 NOVEL BIOTIN-SPECIFIC MONOCLONAL ANTIBODY AND USE THEREOF BTD, IGLV6-57, VSIR TDP1 4750/4885ABL1 3134/4885IDE 553/4885
US-12360108-B2 Biotin-specific monoclonal antibody and use thereof BTD, IGLV6-57, VIM TDP1 4556/4885ABL1 1338/4885IDE 522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.