SCHEMBL3423752

SCHEMBL3423752

O=C(O)CCCCC1SC[C@H]2[C@@H]1NC(=O)N2C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 7/20 0.58
ABL1 P00519 2/20 0.58
IDE P14735 2/20 0.58
RIN1 Q13671 2/20 0.58
MEN1 O00255 1/20 0.58
LMNA P02545 1/20 0.58
PKM P14618 1/20 0.58
MAPK1 P28482 1/20 0.58
KMT2A Q03164 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
HLCS P50747 5/20 0.38
PPARG P37231 1/20 0.37
NR2E3 Q9Y5X4 1/20 0.37
NCOR2 Q9Y618 1/20 0.37
NPSR1 Q6W5P4 1/20 0.34
CA12 O43570 3/20 0.34
CA1 P00915 3/20 0.34
CA2 P00918 3/20 0.34
CA9 Q16790 3/20 0.34
CYP2C9 P11712 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31297012 0.86 TDP1 (0.52) TDP1ABL1IDERIN1MEN1
SCHEMBL21493643 0.86 TDP1 (0.52) TDP1ABL1IDERIN1MEN1
SCHEMBL565813 0.84 TDP1 (0.65) TDP1ABL1IDERIN1MEN1
SCHEMBL7169914 0.84 TDP1 (0.50) TDP1ABL1IDERIN1MEN1
SCHEMBL19751767 0.84 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL19751635 0.84 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL18386701 0.84 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL4967996 0.84 TDP1 (0.58) TDP1ABL1IDERIN1MEN1
SCHEMBL12642068 0.83 TDP1 (0.56) TDP1ABL1IDERIN1MEN1
SCHEMBL30107625 0.82 TDP1 (0.74) TDP1ABL1IDERIN1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2026-05-21 US disclosed
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL DIASOME PHARMACEUTICALS INC (US) 2026-05-07 US disclosed
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS DIASOME PHARMACEUTICALS INC (US) 2025-09-18 US disclosed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP disclosed
EP-2552202-B1 METHODS AND COMPOSITIONS FOR WEIGHT LOSS SDG INC (US) 2023-07-26 EP disclosed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 US disclosed
US-11517529-B2 Orally bioavailable lipid-based constructs SDG, INC. (US) 2022-12-06 US disclosed
US-20220110870-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2022-04-14 US disclosed
EP-3391876-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2021-03-10 EP disclosed
EP-3391876-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2021-03-10 EP disclosed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 US disclosed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 US disclosed
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL SDG, INC. 2010-05-27 US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs SDG, INC. 2010-04-01 US disclosed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US disclosed
US-20090087479-A1 Orally bioavailable lipid-based constructs SDG, INC. ( AN OHIO CORPORATION) (US) 2009-04-02 US disclosed
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal SDG, INC. 2007-09-20 US disclosed
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal SDG, INC. 2007-09-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218117-A1 Supra molecular construct for delivery of interferon to a mammal HAVCR2, IFNAR1, MSR1 TDP1 4728/4885ABL1 2979/4885IDE 221/4885
US-20100080773-A1 Orally Bioavailable Lipid-Based Constructs FABP2, FABP1, LIPC TDP1 4742/4885ABL1 3308/4885IDE 646/4885
US-20100129428-A1 SUPRA MOLECULAR CONSTRUCT FOR DELIVERY OF INTERFERON TO A MAMMAL HAVCR2, IFNAR1, IFNG TDP1 4713/4885ABL1 2883/4885IDE 183/4885
US-20250288521-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, FABP6 TDP1 4819/4885ABL1 4375/4885IDE 422/4885
US-20260137621-A1 ORALLY BIOAVAILABLE LIPID-BASED CONSTRUCTS FABP2, FABP1, SGMS2 TDP1 4755/4885ABL1 4626/4885IDE 1191/4885
US-20220110870-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL INSR, IAPP, GPR119 TDP1 4882/4885ABL1 3769/4885IDE 7/4885
US-20260124139-A1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL GPR119, INSR, FABP1 TDP1 4833/4885ABL1 4576/4885IDE 31/4885
US-11517529-B2 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 TDP1 4819/4885ABL1 4375/4885IDE 422/4885
US-20090087479-A1 Orally bioavailable lipid-based constructs FABP2, FABP1, FABP6 TDP1 4757/4885ABL1 3225/4885IDE 583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.