Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.32 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.32 |
| ▸ | ITGAL | P20701 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197762 | 0.97 | CA1 (0.33) | TRPA1CA1CA2ITGB2ICAM1 | |
| SCHEMBL27656907 | 0.95 | — | — | |
| SCHEMBL2258569 | 0.75 | — | — | |
| SCHEMBL1399575 | 0.65 | NOS1 (0.35) | — | |
| SCHEMBL207535 | 0.65 | AHR (0.42) | AHRALDH1A1CYP2A6IMPDH2 | |
| SCHEMBL2971945 | 0.65 | KDM4E (0.35) | ALDH1A1CYP2A6IMPDH2 | |
| SCHEMBL207776 | 0.65 | AHR (0.42) | AHRALDH1A1 | |
| SCHEMBL208707 | 0.65 | AHR (0.42) | AHR | |
| SCHEMBL3353907 | 0.65 | ALDH1A1 (0.41) | AHRALDH1A1GPR3HSD17B10CYP2A6 | |
| SCHEMBL1091810 | 0.65 | NPSR1 (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989336-B | Metal complexes comprising amidine and indole fused cyclopentadienyl ligands | 阿朗新科荷兰有限公司 | 2023-07-07 | — | — | CN | disclosed |
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | ARLANXEO NETHERLANDS B.V. | 2023-01-24 | — | — | US | disclosed |
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| CN-111989336-A | Metal complexes comprising amidine and indole fused cyclopentadienyl ligands | 阿朗新科荷兰有限公司 | 2020-11-24 | — | — | CN | disclosed |
| WO-2019201838-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019203676-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
| CN-1145370-A | Olefin polymerization catalyst and process for producing polyolefin using the same | SUMITOMO CHEMICAL CO (JP) | 1997-03-19 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11560394-B2 | Metal complex comprising amidine and indole fused cyclopentadienyl ligands | C5, C1S, CLIC4 | TRPA1 422/4885CA1 1176/4885CA2 642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.