SCHEMBL21494515

SCHEMBL21494515

CC1=C(C)C(C)c2c1n(-c1ccccc1)c1ccccc21

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
IL1R1 P14778 1/20 0.40
HTT P42858 2/20 0.39
ALDH1A1 P00352 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 2/20 0.39
SIGMAR1 Q99720 1/20 0.39
LMNA P02545 1/20 0.38
PKM P14618 1/20 0.38
MAPK8 P45983 2/20 0.37
PGR P06401 2/20 0.36
PLA2G2A P14555 1/20 0.35
CYP1A2 P05177 1/20 0.34
GLA P06280 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30209850 1.00 L3MBTL1 (0.47) L3MBTL1KDM4EATMIL1R1HTT
SCHEMBL30028818 0.84 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
SCHEMBL21500046 0.84 IL1R1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
SCHEMBL30027520 0.82 L3MBTL1 (0.44) L3MBTL1KDM4EATMIL1R1HTT
SCHEMBL30027498 0.82 L3MBTL1 (0.44) L3MBTL1KDM4EATMIL1R1HTT
Hydrochloric Acid SCHEMBL28896012 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
Hydrochloric Acid SCHEMBL30028162 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
Hydrochloric Acid SCHEMBL30027860 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
Hydrochloric Acid SCHEMBL28896128 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT
SCHEMBL30028086 0.81 L3MBTL1 (0.43) L3MBTL1KDM4EATMIL1R1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12486342-B2 Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2025-12-02 US disclosed
EP-4139320-B1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS INTERNATIONAL SA (CH) 2025-08-20 EP disclosed
US-20230235100-A1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-07-27 US disclosed
US-20230235100-A1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-07-27 US disclosed
US-20230235100-A1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2023-07-27 US disclosed
CN-111989336-B Metal complexes comprising amidine and indole fused cyclopentadienyl ligands 阿朗新科荷兰有限公司 2023-07-07 CN disclosed
US-11560394-B2 Metal complex comprising amidine and indole fused cyclopentadienyl ligands ARLANXEO NETHERLANDS B.V. 2023-01-24 US disclosed
WO-2021214612-A1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES NOVA CHEMICALS (INTERNATIONAL) S.A. (CH) 2021-10-28 WO disclosed
EP-3781582-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS Arlanxeo Netherlands B.V. (NL) 2021-02-24 EP disclosed
CN-111989336-A Metal complexes comprising amidine and indole fused cyclopentadienyl ligands 阿朗新科荷兰有限公司 2020-11-24 CN disclosed
WO-2019203676-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2019-10-24 WO disclosed
WO-2019203676-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2019-10-24 WO disclosed
WO-2019201838-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2019-10-24 WO disclosed
WO-2019201838-A1 METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS ARLANXEO NETHERLANDS B.V. (NL) 2019-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11560394-B2 Metal complex comprising amidine and indole fused cyclopentadienyl ligands C5, C1S, CLIC4 L3MBTL1 589/4885KDM4E 1589/4885ATM 4468/4885
US-12486342-B2 Cyclopentadienyl/adamantyl phosphinimine zirconium and hafnium complexes HCFC1, AP1M1, AP3M1 L3MBTL1 1310/4885KDM4E 4284/4885ATM 774/4885
US-20230235100-A1 CYCLOPENTADIENYL/ADAMANTYL PHOSPHINIMINE ZIRCONIUM AND HAFNIUM COMPLEXES HCFC1, AP1M1, AP3M1 L3MBTL1 1310/4885KDM4E 4284/4885ATM 774/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.