Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30027860 | 1.00 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| SCHEMBL30209850 | 0.81 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| SCHEMBL21494515 | 0.81 | L3MBTL1 (0.47) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28896160 | 0.80 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30028162 | 0.80 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL28896128 | 0.80 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30027690 | 0.80 | L3MBTL1 (0.43) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL30028218 | 0.79 | L3MBTL1 (0.42) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| SCHEMBL30027498 | 0.78 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMIL1R1ALDH1A1 | |
| SCHEMBL30027520 | 0.78 | L3MBTL1 (0.44) | L3MBTL1KDM4EATMIL1R1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115400797-A | Heteroatom-containing metallocene catalyst system and method for catalyzing alpha-olefin oligomerization | 中国科学院山西煤炭化学研究所 | 2022-11-29 | — | — | CN | claimed |
| CN-115400797-A | Heteroatom-containing metallocene catalyst system and method for catalyzing alpha-olefin oligomerization | 中国科学院山西煤炭化学研究所 | 2022-11-29 | — | — | CN | disclosed |