Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608737 | 0.91 | POLB (0.54) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494552 | 0.91 | POLB (0.56) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL30577232 | 0.91 | POLB (0.54) | POLBLMNAMAPTHTTL3MBTL1 | |
| Bromide SCHEMBL1930790 | 0.90 | POLB (0.55) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494519 | 0.79 | LMNA (0.57) | POLBLMNAMAPTHTTL3MBTL1 | |
| Bromide SCHEMBL16949950 | 0.78 | LMNA (0.56) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494512 | 0.77 | POLB (0.56) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL28922624 | 0.72 | NPC1 (0.61) | POLBLMNAHTTKMT2AMEN1 | |
| SCHEMBL28487426 | 0.72 | NPC1 (0.39) | POLBLMNAMAPTHTTKMT2A | |
| SCHEMBL21494517 | 0.72 | MEN1 (0.51) | POLBLMNAMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781582-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | Arlanxeo Netherlands B.V. (NL) | 2021-02-24 | — | — | EP | disclosed |
| WO-2019203676-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |
| WO-2019201838-A1 | METAL COMPLEX COMPRISING AMIDINE AND INDOLE FUSED CYCLOPENTADIENYL LIGANDS | ARLANXEO NETHERLANDS B.V. (NL) | 2019-10-24 | — | — | WO | disclosed |