Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608737 | 1.00 | POLB (0.54) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494543 | 0.91 | POLB (0.49) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494512 | 0.84 | POLB (0.56) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494552 | 0.79 | POLB (0.56) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL28487426 | 0.79 | NPC1 (0.39) | POLBLMNAMAPTHTTKMT2A | |
| SCHEMBL29031638 | 0.79 | LMNA (0.36) | POLBLMNAMAPTHTTL3MBTL1 | |
| Bromide SCHEMBL1930790 | 0.78 | POLB (0.55) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494571 | 0.76 | POLB (0.50) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL21494517 | 0.76 | MEN1 (0.51) | POLBLMNAMAPTHTTL3MBTL1 | |
| SCHEMBL17608730 | 0.74 | RAB9A (0.61) | POLBLMNAMAPTHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111989336-B | Metal complexes comprising amidine and indole fused cyclopentadienyl ligands | 阿朗新科荷兰有限公司 | 2023-07-07 | — | — | CN | disclosed |