SCHEMBL21496039

SCHEMBL21496039

C[SiH](C)CN1CCNCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
POLB P06746 1/20 0.38
CXCR4 P61073 5/20 0.37
SIGMAR1 Q99720 3/20 0.35
CHRM5 P08912 1/20 0.35
CHRM3 P20309 1/20 0.35
LMNA P02545 1/20 0.34
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CHRM2 P08172 2/20 0.32
MEN1 O00255 1/20 0.32
CHRM1 P11229 1/20 0.32
ADRA2C P18825 1/20 0.32
CCR2 P41597 1/20 0.32
CXCL12 P48061 1/20 0.32
BLM P54132 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29073089 0.85
SCHEMBL28008798 0.73 SMN1; SMN2 (0.38) SMN1; SMN2POLBCXCR4SIGMAR1CHRM5
SCHEMBL14128016 0.72 HRH3 (0.39) POLBCHRM5LMNAMEN1ADRA2C
SCHEMBL25570987 0.72 CXCR4 (0.50) SMN1; SMN2POLBCXCR4SIGMAR1CHRM5
SCHEMBL537898 0.70 SMN1; SMN2 (0.36) SMN1; SMN2POLBCXCR4SIGMAR1CHRM5
SCHEMBL5943 0.69
SCHEMBL447924 0.69
SCHEMBL15866606 0.69
SCHEMBL1332129 0.69
SCHEMBL152746 0.69 SMN1; SMN2 (0.42) SMN1; SMN2POLBCXCR4SIGMAR1CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019202796-A1 POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR 信越化学工業株式会社 2019-10-24 WO disclosed