Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL538867 | 0.84 | SMN1; SMN2 (0.34) | SMN1; SMN2SIGMAR1POLBSLC6A4 | |
| SCHEMBL774158 | 0.80 | SMN1; SMN2 (0.38) | SMN1; SMN2SIGMAR1POLBCXCR4 | |
| SCHEMBL28008798 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2SIGMAR1POLBCXCR4CHRM5 | |
| SCHEMBL4065756 | 0.77 | CXCR4 (0.43) | SMN1; SMN2SIGMAR1POLBCXCR4CHRM5 | |
| SCHEMBL2403147 | 0.76 | CXCR4 (0.44) | SMN1; SMN2SIGMAR1POLBCXCR4 | |
| SCHEMBL1859824 | 0.75 | TSHR (0.37) | SMN1; SMN2SIGMAR1POLBCYP1A2CHRM2 | |
| SCHEMBL4060922 | 0.74 | SMN1; SMN2 (0.41) | SMN1; SMN2POLBCHRM5CHRM3 | |
| SCHEMBL27902254 | 0.74 | — | — | |
| Methylpiperazine SCHEMBL557567 | 0.72 | PHGDH (0.34) | SIGMAR1 | |
| SCHEMBL29039659 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111440321-B | Multifunctional alkoxy-terminated polysiloxane polymer and preparation method thereof | 浙江新安化工集团股份有限公司 | 2021-04-30 | — | — | CN | disclosed |
| US-9074032-B2 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2015-07-07 | — | — | US | disclosed |
| EP-2414411-B1 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2013-02-20 | — | — | EP | disclosed |
| US-8137590-B2 | Particles comprising zwitterionic structural elements | WACKER CHEMIE AG (DE) | 2012-03-20 | — | — | US | disclosed |
| US-20120031843-A1 | Membranes based on polyvinyl alcohol | WACKER CHEMIE AG (DE) | 2012-02-09 | — | — | US | disclosed |
| EP-2414411-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | Wacker Chemie AG (DE) | 2012-02-08 | — | — | EP | disclosed |
| EP-1940940-B1 | PARTICLES COMPRISING ZWITTERIONIC STRUCTURAL ELEMENTS | CONSORTIUM ELEKTROCHEM IND (DE) | 2011-04-20 | — | — | EP | disclosed |
| WO-2010112372-A2 | MEMBRANES BASED ON POLYVINYL ALCOHOL | WACKER CHEMIE AG (DE) | 2010-10-07 | — | — | WO | disclosed |
| US-20080286628-A1 | Particles Comprising Zwitterionic Structural Elements | WACKER CHEMIE AG (DE) | 2008-11-20 | — | — | US | disclosed |
| WO-2008015123-A1 | PREPARATION OF ACID DERIVATIVE-FUNCTIONAL ORGANOSILICON COMPOUNDS | WACKER CHEMIE AG (DE) | 2008-02-07 | — | — | WO | disclosed |
| WO-2008015120-A1 | λ5-Si - SILICATE-FUNCTIONAL PREPOLYMERS | WACKER CHEMIE AG (DE) | 2008-02-07 | — | — | WO | disclosed |