SCHEMBL28008798

SCHEMBL28008798

CO[SiH](CN1CCNCC1)OC

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.38
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
SLC6A4 P31645 1/20 0.35
OPRD1 P41143 1/20 0.35
OPRK1 P41145 1/20 0.35
POLB P06746 1/20 0.34
APOBEC3A P31941 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34
APOBEC3G Q9HC16 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
CXCR4 P61073 2/20 0.33
SIGMAR1 Q99720 3/20 0.32
CHRM5 P08912 1/20 0.32
CHRM3 P20309 1/20 0.32
LMNA P02545 1/20 0.32
PDE4A P27815 1/20 0.31
PDE4B Q07343 1/20 0.31
PDE4C Q08493 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29030826 0.78 POLB (0.41) SMN1; SMN2CYP1A2CHRM2SLC6A4OPRD1
SCHEMBL537898 0.78 SMN1; SMN2 (0.36) SMN1; SMN2CYP1A2CHRM2SLC6A4OPRD1
SCHEMBL31187728 0.76 HRH3 (0.35) POLBMEN1KMT2ASIGMAR1CHRM5
SCHEMBL3810144 0.75 CXCR4 (0.46) SMN1; SMN2CHRM2POLBMEN1KMT2A
SCHEMBL538867 0.75 SMN1; SMN2 (0.34) SMN1; SMN2SLC6A4POLBMEN1KMT2A
SCHEMBL2399870 0.74 CXCR4 (0.47) SMN1; SMN2CHRM2POLBMEN1KMT2A
SCHEMBL21496039 0.73 SMN1; SMN2 (0.38) SMN1; SMN2CYP1A2CHRM2SLC6A4OPRD1
SCHEMBL27893859 0.69 ADRB1 (0.33) SIGMAR1LMNAADRB1HTR3EHTR3B
SCHEMBL8320589 0.69
SCHEMBL28393201 0.66 POLB (0.37) SMN1; SMN2SLC6A4POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110191701-B Composition for enhancing protein strength 株式会社LG生活健康 2023-02-21 CN claimed
CN-111363550-A Selective etching liquid composition and preparation method and application thereof 上海新阳半导体材料股份有限公司 2020-07-03 CN claimed
CN-116355222-A Washable amino and polyether co-modified polysiloxane and preparation method thereof 山东东岳有机硅材料股份有限公司 2023-06-30 CN disclosed
CN-110191701-B Composition for enhancing protein strength 株式会社LG生活健康 2023-02-21 CN disclosed
CN-110461948-B Gels comprising condensation products of organosilicon compounds 住友化学株式会社 2021-11-23 CN disclosed
CN-111440321-B Multifunctional alkoxy-terminated polysiloxane polymer and preparation method thereof 浙江新安化工集团股份有限公司 2021-04-30 CN disclosed
CN-111440321-A Multifunctional alkoxy-terminated polysiloxane polymer and preparation method thereof 浙江新安化工集团股份有限公司 2020-07-24 CN disclosed
CN-103030814-B Washable hydrophilic silicone oil and preparation method thereof DONGGUAN JIAHONG SILICON TECHNOLOGY CO LTD 2015-04-29 CN disclosed