Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1069533 | 0.82 | MAPT (0.40) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL4616628 | 0.82 | MAPT (0.40) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL2204713 | 0.80 | MAPT (0.38) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL814026 | 0.79 | KCNH3 (0.41) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL27678660 | 0.78 | NPSR1 (0.39) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL571735 | 0.78 | MAPT (0.40) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL2204709 | 0.77 | MAPT (0.37) | MAPTALDH1A1MAOAMAOBTSHR | |
| SCHEMBL28089433 | 0.75 | MAPT (0.38) | MAPTALDH1A1MAOAMAOBL3MBTL1 | |
| SCHEMBL2721214 | 0.75 | MAPT (0.52) | MAPTALDH1A1L3MBTL1TSHRMEN1 | |
| SCHEMBL29200269 | 0.74 | ALDH1A1 (0.52) | MAPTALDH1A1MAOAMAOBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202796-A1 | POLYMER HAVING REACTIVE SILICON-CONTAINING GROUP AND PRODUCTION METHOD THEREFOR | 信越化学工業株式会社 | 2019-10-24 | — | — | WO | disclosed |