SCHEMBL214972

SCHEMBL214972

Nc1ncnc2c1ncn2[C@]1(P(=O)(O)O)O[C@H](COP(=O)(O)O)[C@@H](O)[C@H]1O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 5/20 0.59
P2RY2 P41231 3/20 0.59
SRC P12931 2/20 0.59
SMN1; SMN2 Q16637 2/20 0.59
DNPH1 O43598 1/20 0.59
PRKAB2 O43741 1/20 0.59
TRPM2 O94759 1/20 0.59
LDHA P00338 1/20 0.59
ADRB2 P07550 1/20 0.59
FBP1 P09467 1/20 0.59
ADORA1 P30542 1/20 0.59
PRKAG1 P54619 1/20 0.59
PRKAA2 P54646 1/20 0.59
PDE4D Q08499 1/20 0.59
KCNH2 Q12809 1/20 0.59
PRKAA1 Q13131 1/20 0.59
PDE3A Q14432 1/20 0.59
TAS1R3 Q7RTX0 1/20 0.59
TAS1R1 Q7RTX1 1/20 0.59
P2RY11 Q96G91 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL668586 0.92 P2RX1 (0.59) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL199259 0.88 ADORA1 (0.51) P2RY1P2RY2SRCSMN1; SMN2DNPH1
Pyrophosphoric Acid SCHEMBL668584 0.87 ADORA1 (0.52) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL10824472 0.87 P2RY1 (0.60) P2RY1P2RY2SRCSMN1; SMN2DNPH1
Phosphoric Acid SCHEMBL216583 0.87 ADORA1 (0.50) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL2791981 0.86 P2RY1 (0.59) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL16108838 0.86 P2RY1 (0.59) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL30195073 0.86 P2RY1 (0.59) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL16700549 0.85 P2RY1 (0.58) P2RY1P2RY2SRCSMN1; SMN2DNPH1
SCHEMBL28769844 0.84 P2RY1 (0.57) P2RY1P2RY2SRCSMN1; SMN2DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118109378-A Coli engineering bacterium for high-yield L-methionine and method for producing L-methionine by full fermentation method thereof 浙江工业大学 2024-05-31 CN disclosed
CN-114846143-A Expression of nitrogenase polypeptides in plant cells 联邦科学技术研究组织 2022-08-02 CN disclosed
CN-114144527-A Expression of nitrogenase polypeptides in plant cells 联邦科学技术研究组织 2022-03-04 CN disclosed
EP-1592813-B1 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BELLBROOK LABS LLC (US) 2012-12-26 EP disclosed
US-8088897-B2 Detecting the activity of and screening acceptor substrates, inhibitors, or activators of enzymes catalyzing group transfer reactions to facilitate the development of more selective and therapeutic drugs BellBrook Labs, Inc. (US) 2012-01-03 US disclosed
US-7847066-B2 High throughput screening; immunoassays; immunogens; antibodies producing uridine diphosphate with higher affinity to carbohydrates BELLBROOK LABS, LLC (US) 2010-12-07 US disclosed
EP-2222708-A1 ASSAY METHOD FOR GROUP TRANSFER REACTIONS Bellbrook Labs, Llc (US) 2010-09-01 EP disclosed
US-20090186358-A1 Pathway Analysis of Cell Culture Phenotypes and Uses Thereof WYETH (US) 2009-07-23 US disclosed
WO-2009078876-A1 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BELLBROOK LABS, LLC (US) 2009-06-25 WO disclosed
US-20080255341-A2 ASSAY METHOD FOR GROUP TRANSFER REACTIONS LOWERY ROBERT 2008-10-16 US disclosed
US-7355010-B2 Assay method for group transfer reactions BELLBROOK LABS, LLC (US) 2008-04-08 US disclosed
US-7332278-B2 Assay methods for group transfer reactions BELLBROOK LABS, LLC (US) 2008-02-19 US disclosed
EP-1869083-A1 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BellBrook Labs, LLC (US) 2007-12-26 EP disclosed
WO-2006127008-A1 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BELLBROOK LABS, LLC (US) 2006-11-30 WO disclosed
US-20060172335-A1 Assay method for group transfer reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2006-08-03 US disclosed
EP-1592813-A4 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BELLBROOK LABS LLC (US) 2006-06-14 EP disclosed
EP-1592813-A2 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BellBrook Labs, LLC (US) 2005-11-09 EP disclosed
US-20050239142-A1 Assay method for group transfer reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2005-10-27 US disclosed
US-20040219510-A1 Assay method for group transfer reactions NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2004-11-04 US disclosed
WO-2004068115-A2 ASSAY METHOD FOR GROUP TRANSFER REACTIONS BELLBROOK LABS, LLC (US) 2004-08-12 WO disclosed