Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | P2RY2 | P41231 | 4/20 | 0.48 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.46 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.46 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.46 |
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.46 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.46 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.46 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.46 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL199259 | 0.95 | ADORA1 (0.51) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| Phosphoric Acid SCHEMBL216583 | 0.94 | ADORA1 (0.50) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| SCHEMBL15665475 | 0.92 | ADORA1 (0.52) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| SCHEMBL668586 | 0.88 | P2RX1 (0.59) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| SCHEMBL214972 | 0.87 | P2RY1 (0.59) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| SCHEMBL8572697 | 0.83 | ADORA1 (0.38) | ADORA1SMN1; SMN2ADORA3ADORA2ADPP4 | |
| Adenosine SCHEMBL14783412 | 0.83 | P2RY2 (0.65) | ADORA1P2RY2P2RY1SMN1; SMN2SRC | |
| SCHEMBL13738525 | 0.83 | ADORA1 (0.38) | ADORA1SMN1; SMN2ADORA3ADORA2ADPP4 | |
| SCHEMBL27971039 | 0.83 | FDPS (0.42) | ADORA1SMN1; SMN2ADORA3ADORA2ADPP4 | |
| Pyrophosphoric Acid SCHEMBL18486727 | 0.82 | ADORA1 (0.48) | ADORA1P2RY2P2RY1SMN1; SMN2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023230560-A1 | TREATMENT OF ORGANIC ACIDEMIAS OR PANTOTHENATE KINASE ASSOCIATED NEURODEGENERATION WITH MODULATORS OF PANTOTHENATE KINASES | COA THERAPEUTICS, INC. (US) | 2023-11-30 | — | — | WO | disclosed |
| US-10208270-B2 | Acyltransferases and uses thereof in fatty acid production | BASF PLANT SCIENCE COMPANY GMBH (DE) | 2019-02-19 | — | — | US | disclosed |
| EP-2585603-B1 | ACYLTRANSFERASES AND USES THEROF IN FATTY ACID PRODUCTION | BASF PLANT SCIENCE CO GMBH (DE) | 2017-12-20 | — | — | EP | disclosed |
| US-20160272951-A1 | ACYLTRANSFERASES AND USES THEREOF IN FATTY ACID PRODUCTION | BASF PLANT SCIENCE COMPANY GMBH (DE) | 2016-09-22 | — | — | US | disclosed |
| US-9388437-B2 | Acyltransferases and uses thereof in fatty acid production | BASF PLANT SCIENCE COMPANY GMBH (DE) | 2016-07-12 | — | — | US | disclosed |
| EP-2585603-A1 | ACYLTRANSFERASES AND USES THEROF IN FATTY ACID PRODUCTION | BASF Plant Science Company GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20130097733-A1 | Acyltransferases and Uses Thereof in Fatty Acid Production | BASF PLANT SCIENCE COMPANY GMBH (DE) | 2013-04-18 | — | — | US | disclosed |
| WO-2012024189-A2 | COMPOSITIONS AND METHODS FOR DETERMINING PREDISPOSITION TO DEVELOPING METABOLIC SYNDROME | THE J. DAVID GLADSTONE INSTITUTES (US) | 2012-02-23 | — | — | WO | disclosed |
| WO-2011161093-A1 | ACYLTRANSFERASES AND USES THEROF IN FATTY ACID PRODUCTION | BASF PLANT SCIENCE COMPANY GMBH (DE) | 2011-12-29 | — | — | WO | disclosed |