Pyrazine

Pyrazine

SCHEMBL21497224

c1cnccn1.c1cocn1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxazole SCHEMBL29728171 0.93
Oxazole SCHEMBL1743576 0.93
Oxazole SCHEMBL14 0.93
Oxazole SCHEMBL983076 0.90
Oxazole SCHEMBL7538737 0.90
Oxazole SCHEMBL986132 0.90
Oxazole SCHEMBL1128503 0.90
Oxazole SCHEMBL9452923 0.90
Oxazole SCHEMBL5199619 0.90
Oxazole SCHEMBL6315939 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113559006-A A cosmetic composition for scavenging free radicals and resisting aging 河南农业大学 2021-10-29 CN claimed
CN-104603165-B Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound 日本瑞翁株式会社 2017-04-26 CN claimed
CN-103819509-A Preparation method for novel Ru (II) complex containing-benzobenzoxazole and pyrazino [1,10] phenanthroline and anticancer activity of novel Ru (II) complex UNIV JIANGNAN 2014-05-28 CN claimed
CN-116650370-A Skin-delaying composition and skin care product 广州天然国度生物科技有限公司 2023-08-29 CN disclosed
US-11708376-B2 Substituted imidazo[4,5-b]pyridines, imidazo[4,5-b]pyrazines, and oxazolo[4,5- b]pyrazines as mitochondrial uncouplers VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2023-07-25 US disclosed
CN-116473883-A Anti-aging composition and preparation method and application thereof 广州凡岛网络科技有限公司 2023-07-25 CN disclosed
CN-113559006-B A cosmetic composition for scavenging free radicals and resisting aging 河南农业大学 2022-09-20 CN disclosed
CN-113559006-B A cosmetic composition for scavenging free radicals and resisting aging 河南农业大学 2022-09-20 CN disclosed
CN-113559006-A A cosmetic composition for scavenging free radicals and resisting aging 河南农业大学 2021-10-29 CN disclosed
CN-113559006-A A cosmetic composition for scavenging free radicals and resisting aging 河南农业大学 2021-10-29 CN disclosed
US-20210238181-A1 IMIDAZOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2021-08-05 US disclosed
EP-3781567-A1 IMIDAZOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS Virginia Tech Intellectual Properties, Inc. (US) 2021-02-24 EP disclosed
CN-112262141-A Imidazopyridines useful as mitochondrial uncouplers 弗吉尼亚理工大学知识产权有限公司 2021-01-22 CN disclosed
WO-2019204816-A1 IMIDAZOPYRIDINES USEFUL AS MITOCHONDRIAL UNCOUPLERS VIRGINIA TECH INTELLECTUAL PROPERTIES, INC. (US) 2019-10-24 WO disclosed
CN-104603165-B Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound 日本瑞翁株式会社 2017-04-26 CN disclosed
CN-105452311-A Polymerizable compound, polymerizable composition, polymer, and optically anisotropic body ZEON CORP 2016-03-30 CN disclosed
CN-104603165-A Polymerizable compound, polymerizable composition, polymer, optically anisotropic body, and method for producing polymerizable compound ZEON CORP 2015-05-06 CN disclosed
CN-103819509-A Preparation method for novel Ru (II) complex containing-benzobenzoxazole and pyrazino [1,10] phenanthroline and anticancer activity of novel Ru (II) complex UNIV JIANGNAN 2014-05-28 CN disclosed
CN-103732065-A Benzofuran compounds for the treatment of hepatitis c virus infections GLAXO GROUP LTD 2014-04-16 CN disclosed