Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.39 |
| ▸ | MET | P08581 | 6/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25515395 | 0.89 | GNRHR (0.35) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL23190476 | 0.87 | ALDH1A1 (0.40) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL20932780 | 0.86 | ALDH1A1 (0.39) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL25054101 | 0.85 | ALDH1A1 (0.40) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL28091363 | 0.80 | ALDH1A1 (0.53) | ALDH1A1KDM4ETP53HSP90AA1HSP90AB1 | |
| SCHEMBL24657653 | 0.79 | GNRHR (0.39) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL264293 | 0.78 | ALDH1A1 (0.58) | ALDH1A1KDM4ETP53HSP90AA1HSP90AB1 | |
| SCHEMBL26315520 | 0.77 | ALDH1A1 (0.39) | GNRHRALDH1A1KDM4ETP53HSP90AA1 | |
| SCHEMBL19341334 | 0.77 | KCNH2 (0.40) | ALDH1A1KDM4EMAPTHTTSMN1; SMN2 | |
| SCHEMBL9969439 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ETP53HSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10450286-B2 | Compounds and compositions for inhibition of FASN | FORMA THERAPEUTICS, INC. (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10450286-B2 | Compounds and compositions for inhibition of FASN | FASN, FABP1, SCD | GNRHR 4154/4885ALDH1A1 1393/4885KDM4E 4280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.