Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2148965 | 0.86 | HDAC1 (0.31) | — | |
| SCHEMBL2149199 | 0.83 | ALDH1A1 (0.36) | — | |
| SCHEMBL2149462 | 0.79 | — | — | |
| SCHEMBL2148940 | 0.79 | — | — | |
| SCHEMBL3244707 | 0.79 | KMT2A (0.38) | — | |
| SCHEMBL3236146 | 0.79 | BRD4 (0.31) | — | |
| SCHEMBL2312069 | 0.77 | P2RY14 (0.39) | PTGDR2 | |
| SCHEMBL2314611 | 0.75 | CYP1A2 (0.36) | PTGDR2 | |
| SCHEMBL2149678 | 0.73 | — | — | |
| SCHEMBL3230025 | 0.73 | PTGDR2 (0.35) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342182-A1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | H. Lundbeck A/S (DK) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010028655-A1 | ISOQUINOLINONE DERIVATIVES AS NK3 ANTAGONISTS | H. LUNDBECK A/S (DK) | 2010-03-18 | — | — | WO | disclosed |