Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.72 |
| ▸ | LMNA | P02545 | 6/20 | 0.72 |
| ▸ | TP53 | P04637 | 2/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | USP2 | O75604 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7292316 | 0.88 | MAPT (0.69) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL26546756 | 0.81 | KDR (0.76) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL12139485 | 0.79 | HPGD (0.74) | MAPTLMNAALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL13250942 | 0.79 | SMN1; SMN2 (1.00) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL4443052 | 0.78 | KDR (0.71) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL13004812 | 0.78 | KDR (0.71) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL12139490 | 0.78 | HPGD (0.71) | LMNAALDH1A1SMN1; SMN2HPGDHTT | |
| SCHEMBL5804247 | 0.77 | KDR (0.69) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL5804246 | 0.77 | KDR (0.69) | MAPTLMNATP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL14422910 | 0.77 | KDR (0.69) | MAPTLMNATP53ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10448632-B2 | Control of plant stress tolerance, water use efficiency and gene expression using novel ABA receptor synthetic agonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2019-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10448632-B2 | Control of plant stress tolerance, water use efficiency and gene expression using novel ABA receptor synthetic agonists | NPBWR1, AVPR1A, AAK1 | MAPT 4664/4885LMNA 4858/4885TP53 2771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.