Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | ESRRG | P62508 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 15/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.46 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 6/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214985 | 1.00 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL214237 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL214236 | 0.83 | ALDH1A1 (0.57) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL213227 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL213228 | 0.81 | ALDH1A1 (0.50) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL214984 | 0.79 | LMNA (0.44) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL214983 | 0.79 | LMNA (0.44) | ALDH1A1GAAMAPTKMT2AMEN1 | |
| SCHEMBL213269 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL213268 | 0.75 | ALDH1A1 (0.51) | ALDH1A1KDM4EGAAESRRGMAPT | |
| SCHEMBL214587 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KDM4EGAAESRRGMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | claimed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | claimed |
| US-8088868-B2 | oximation of cojugated homopolymers formed by addtion polymerization of conjugated diene monomer in the presence lanthanide copmpounds as polymerization catalysts; polymers used in the manufacture of tires having reduced hysteresis | BRIDGESTONE CORPORATION (JP) | 2012-01-03 | — | — | US | disclosed |
| US-20080146745-A1 | POLYMERS FUNCTIONALIZED WITH PROTECTED OXIME COMPOUNDS | BRIDGESTONE CORPORATION (JP) | 2008-06-19 | — | — | US | disclosed |