Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | SCD | O00767 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21500519 | 0.84 | HDAC11 (0.63) | HDAC11 | |
| SCHEMBL21496753 | 0.79 | HDAC11 (0.72) | HDAC11HRH3CRBNDDB1 | |
| SCHEMBL21496672 | 0.71 | HDAC11 (0.48) | HDAC11HRH3CRBNDDB1SCD | |
| SCHEMBL21500527 | 0.66 | HDAC11 (0.63) | HDAC11 | |
| SCHEMBL21500534 | 0.65 | HDAC11 (0.48) | HDAC11TIPARP | |
| SCHEMBL21500532 | 0.65 | HDAC11 (0.46) | HDAC11TIPARP | |
| SCHEMBL16896582 | 0.64 | SMN1; SMN2 (0.61) | HRH3CRBNDDB1SCD | |
| SCHEMBL8096748 | 0.64 | HRH3 (0.60) | HRH3CRBNDDB1SCD | |
| SCHEMBL29505245 | 0.64 | SMN1; SMN2 (0.61) | HRH3CRBNDDB1SCD | |
| SCHEMBL21500496 | 0.62 | HDAC11 (1.00) | HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204550-A1 | ISOINDOLINES AS HDAC INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |