Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.46 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TNKS | O95271 | 4/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 4/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21500452 | 0.81 | HDAC11 (0.41) | HDAC11TIPARP | |
| SCHEMBL23771348 | 0.81 | HDAC11 (0.41) | HDAC11TIPARP | |
| SCHEMBL21500462 | 0.78 | HDAC11 (0.72) | HDAC11HDAC6ALDH1A1HPGD | |
| SCHEMBL21500527 | 0.78 | HDAC11 (0.63) | HDAC11HDAC6 | |
| Hydrochloric Acid SCHEMBL23751077 | 0.77 | HDAC11 (0.71) | HDAC11HDAC6ALDH1A1HPGD | |
| SCHEMBL21500534 | 0.74 | HDAC11 (0.48) | HDAC11TIPARPHDAC6 | |
| SCHEMBL21500519 | 0.67 | HDAC11 (0.63) | HDAC11ALDH1A1 | |
| SCHEMBL23771282 | 0.66 | TIPARP (0.36) | HDAC11TIPARP | |
| SCHEMBL21496640 | 0.65 | HDAC11 (0.68) | HDAC11HDAC6 | |
| SCHEMBL21500518 | 0.65 | HDAC11 (0.44) | HDAC11TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204550-A1 | ISOINDOLINES AS HDAC INHIBITORS | FORMA THERAPEUTICS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |