Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.41 |
| ▸ | DRD4 | P21917 | 4/20 | 0.41 |
| ▸ | DRD3 | P35462 | 4/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | CCR4 | P51679 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052184 | 0.78 | DRD2 (0.55) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL3190996 | 0.71 | MAOA (0.37) | SMN1; SMN2NPC1RAB9AMAOBHPGD | |
| SCHEMBL30392289 | 0.71 | MAOA (0.37) | SMN1; SMN2NPC1RAB9AMAOBHPGD | |
| SCHEMBL26159938 | 0.66 | TDP1 (0.34) | SMN1; SMN2NPC1RAB9AMAOBHPGD | |
| SCHEMBL26042290 | 0.66 | MAOA (0.37) | SMN1; SMN2MAOB | |
| SCHEMBL28729990 | 0.66 | HTR2C (0.45) | DRD2DRD3HTR2ASMN1; SMN2NPC1 | |
| SCHEMBL29576970 | 0.66 | HTR2C (0.45) | DRD2DRD3HTR2ASMN1; SMN2NPC1 | |
| SCHEMBL22858606 | 0.66 | DRD2 (0.48) | DRD2DRD4DRD3HTR2ADRD1 | |
| SCHEMBL21500751 | 0.65 | SMN1; SMN2 (0.32) | HTR2ASMN1; SMN2NPC1RAB9AMAOB | |
| SCHEMBL5547659 | 0.64 | MAOA (0.41) | DRD2DRD4DRD3DRD1DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019202140-A1 | PROCESS FOR DYEING KERATIN FIBRES COMPRISING THE APPLICATION OF A CHROMENOL/CHROMEN-2-ONE DERIVATIVE, COMPOSITION AND DEVICE | L'OREAL (FR) | 2019-10-24 | — | — | WO | disclosed |