SCHEMBL21500873

SCHEMBL21500873

Oc1ccc(Oc2c(I)cc(I)cc2I)cc1

nearest known ligand 0.62

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PCNA P12004 13/20 0.57
LIG1 P18858 1/20 0.55
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
ESR1 P03372 1/20 0.52
ESR2 Q92731 1/20 0.52
LTA4H P09960 2/20 0.45
NR1H2 P55055 1/20 0.45
BAX Q07812 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25773017 0.84 PCNA (0.54) PCNALIG1MEN1KMT2AESR1
SCHEMBL16124480 0.81 PCNA (0.63) PCNALIG1
SCHEMBL4005004 0.81 PCNA (0.66) PCNALIG1
SCHEMBL4008454 0.80 PCNA (0.61) PCNALIG1
SCHEMBL14485265 0.80 PCNA (0.64) PCNALIG1
SCHEMBL24414010 0.78 MEN1 (0.64) MEN1KMT2AESR1ESR2LTA4H
SCHEMBL24021497 0.78 PCNA (0.38) PCNALIG1MEN1KMT2A
SCHEMBL24413695 0.77 TPMT (0.50) PCNAKMT2A
SCHEMBL14264010 0.77 PCNA (0.67) PCNALIG1
SCHEMBL22382794 0.77 PCNA (0.67) PCNALIG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2022-05-12 US disclosed
US-11156916-B2 Resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2021-10-26 US disclosed
US-20190324368-A1 RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2019-10-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220146930-A1 SALT, ACID GENERATOR, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN RER1, FGFR1, NHERF1 PCNA 1880/4885LIG1 3140/4885MEN1 2209/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.