Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520494 | 1.00 | LMNA (0.31) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL15372562 | 1.00 | LMNA (0.31) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL12797870 | 0.96 | — | — | |
| SCHEMBL22618173 | 0.89 | MEN1 (0.40) | MEN1KMT2A | |
| SCHEMBL11514362 | 0.89 | LMNA (0.37) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL24506675 | 0.83 | CES2 (0.31) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL20801430 | 0.83 | LMNA (0.40) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL17168484 | 0.83 | CES2 (0.31) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL762258 | 0.83 | LMNA (0.40) | LMNAMCL1POLBMEN1KMT2A | |
| SCHEMBL27262127 | 0.83 | LMNA (0.40) | LMNAMCL1POLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019201123-A1 | MULTIFUNCTIONAL COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF IN PHARMACEUTICALS | 四川科伦博泰生物医药股份有限公司 | 2019-10-24 | — | — | WO | disclosed |