Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17045326 | 0.80 | ADORA2A (0.34) | — | |
| SCHEMBL21501719 | 0.76 | MPO (0.39) | MPO | |
| SCHEMBL14407691 | 0.72 | MEN1 (0.34) | — | |
| SCHEMBL17045354 | 0.69 | ADORA2A (0.35) | — | |
| SCHEMBL14412255 | 0.68 | HRH2 (0.31) | — | |
| SCHEMBL5229548 | 0.68 | PKM (0.37) | — | |
| SCHEMBL12152251 | 0.68 | ADORA2A (0.36) | — | |
| SCHEMBL5236264 | 0.67 | RET (0.40) | — | |
| SCHEMBL23793833 | 0.62 | KDM4E (0.33) | — | |
| SCHEMBL19635547 | 0.62 | EPHX2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3110818-B1 | 9H-PYRIMIDO[4,5-B]INDOLES AND RELATED ANALOGS AS BET BROMODOMAIN INHIBITORS | UNIV MICHIGAN REGENTS (US) | 2019-10-23 | — | — | EP | disclosed |