Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 5/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | TYMS | P04818 | 2/20 | 0.39 |
| ▸ | ATIC | P31939 | 2/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.38 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.38 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14167626 | 0.98 | NOD1 (0.43) | GARTNOD1TYMSATICFOLH1 | |
| SCHEMBL14167513 | 0.95 | NOD1 (0.46) | GARTNOD1TYMSATICFOLH1 | |
| SCHEMBL14167462 | 0.95 | NOD1 (0.46) | GARTNOD1TYMSATICFOLH1 | |
| SCHEMBL2157922 | 0.88 | NOD1 (0.39) | GARTNOD1TYMSATICFOLH1 | |
| SCHEMBL19051570 | 0.88 | NAALAD2 (0.39) | FOLH1SLC15A2NAALAD2 | |
| SCHEMBL31265388 | 0.87 | SLC15A2 (0.44) | GARTTYMSATICFOLH1SLC15A2 | |
| SCHEMBL29870996 | 0.87 | SLC15A2 (0.44) | GARTTYMSATICFOLH1SLC15A2 | |
| SCHEMBL30716920 | 0.87 | SLC6A5 (0.52) | NOD1FOLH1SLC15A2SLC6A5 | |
| SCHEMBL19051472 | 0.87 | SLC6A5 (0.39) | GARTSLC6A5 | |
| SCHEMBL31265389 | 0.86 | SLC15A2 (0.51) | FOLH1SLC15A2SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340261-A1 | AMYLIN DERIVATIVES | Novo Nordisk A/S (DK) | 2011-07-06 | — | — | EP | claimed |
| WO-2010046357-A1 | AMYLIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2010-04-29 | — | — | WO | claimed |
| EP-2340261-A1 | AMYLIN DERIVATIVES | Novo Nordisk A/S (DK) | 2011-07-06 | — | — | EP | disclosed |
| WO-2010046357-A1 | AMYLIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2010-04-29 | — | — | WO | disclosed |