Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 12/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21496865 | 0.87 | F10 (0.37) | ALDH1A1LMNAPOLBF10 | |
| SCHEMBL21512972 | 0.87 | F10 (0.37) | ALDH1A1LMNAPOLBF10MAPT | |
| SCHEMBL21512973 | 0.84 | F10 (0.38) | ALDH1A1LMNAPOLBF10MAPT | |
| SCHEMBL12136880 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBF10BRD4 | |
| SCHEMBL12136875 | 0.82 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBF10BRD4 | |
| SCHEMBL21512153 | 0.81 | ALDH1A1 (0.47) | ALDH1A1F10 | |
| SCHEMBL21512799 | 0.81 | ALDH1A1 (0.47) | ALDH1A1F10 | |
| SCHEMBL12136948 | 0.81 | BRD4 (0.40) | ALDH1A1LMNAPOLBF10BRD4 | |
| SCHEMBL21512168 | 0.80 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBF10 | |
| SCHEMBL21511818 | 0.80 | ALDH1A1 (0.35) | ALDH1A1LMNAPOLBF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019204505-A2 | K-RAS MODULATORS WITH A VINYL SULFONAMIDE MOIETY | THERAS, INC. (US) | 2019-10-24 | — | — | WO | disclosed |