SCHEMBL21515239

SCHEMBL21515239

c1ccc2c(c1)-c1cccc3cccc(c13)N2c1ccc(-c2nc3ccccc3nc2-c2cccc3c2oc2ccccc23)cc1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PDE6D O43924 1/20 0.40
ALOX5 P09917 2/20 0.37
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
PRKDC P78527 3/20 0.35
PIK3CD O00329 1/20 0.34
PIK3CB P42338 1/20 0.34
CYP1A2 P05177 1/20 0.33
ADK P55263 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GRM4 Q14833 1/20 0.30
KDM4E B2RXH2 2/20 0.30
TP53 P04637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
GAA P10253 1/20 0.30
CDK2 P24941 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21515241 0.88 PDE6D (0.40) PDE6DALOX5NPC1RAB9ACYP1A2
SCHEMBL21515233 0.85 PRKDC (0.36) PDE6DALOX5PRKDCPIK3CDPIK3CB
SCHEMBL21515251 0.85 PDE6D (0.46) PDE6DNPC1RAB9ACYP1A2L3MBTL1
SCHEMBL21515232 0.83 PDE6D (0.44) PDE6DNPC1RAB9ACYP1A2L3MBTL1
SCHEMBL22944958 0.82 ALOX5 (0.36) ALOX5PRKDCPIK3CDPIK3CBCYP1A2
SCHEMBL22945423 0.82 PDE6D (0.46) PDE6DALOX5NPC1RAB9APRKDC
SCHEMBL21515250 0.82 PDE6D (0.57) PDE6DL3MBTL1KDM4EALDH1A1LMNA
SCHEMBL21515427 0.82 PRKDC (0.35) PDE6DALOX5PRKDCPIK3CDPIK3CB
SCHEMBL20259800 0.81 ALOX5 (0.41) PDE6DALOX5NPC1RAB9APRKDC
SCHEMBL22945144 0.81 PDE6D (0.38) PDE6DNPC1RAB9ACYP1A2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11812658-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME LG CHEM, LTD. (KR) 2021-02-04 US disclosed
WO-2019203613-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME 주식회사 엘지화학 2019-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210036236-A1 COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME DRD1, DRD3, DRD2 PDE6D 342/4885ALOX5 386/4885NPC1 2397/4885
US-11812658-B2 Compound and organic light emitting diode comprising same DRD1, DRD3, DRD2 PDE6D 342/4885ALOX5 386/4885NPC1 2397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.