Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | ALPI | P09923 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21519445 | 1.00 | KMT2A (0.52) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519609 | 0.92 | KMT2A (0.53) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519607 | 0.92 | KMT2A (0.53) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519374 | 0.89 | KMT2A (0.46) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519372 | 0.89 | KMT2A (0.46) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519665 | 0.86 | KMT2A (0.58) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519664 | 0.86 | KMT2A (0.58) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519562 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519560 | 0.86 | KMT2A (0.70) | KMT2AALDH1A1LMNAMAPK1SMN1; SMN2 | |
| SCHEMBL21519616 | 0.81 | MAPT (0.53) | KMT2AALDH1A1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006294-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-06-11 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | OPRL1, INA, OGFR | KMT2A 3083/4885ALDH1A1 1048/4885LMNA 1901/4885 |
| US-12006294-B2 | Therapeutic compounds | OPRL1, INA, OGFR | KMT2A 3083/4885ALDH1A1 1048/4885LMNA 1901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.