Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.70 |
| ▸ | MAPT | P10636 | 11/20 | 0.55 |
| ▸ | RAB9A | P51151 | 6/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21519560 | 1.00 | KMT2A (0.70) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519665 | 0.90 | KMT2A (0.58) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519664 | 0.90 | KMT2A (0.58) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519445 | 0.86 | KMT2A (0.52) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519447 | 0.86 | KMT2A (0.52) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519609 | 0.81 | KMT2A (0.53) | KMT2AMAPTRAB9ANPC1GAA | |
| SCHEMBL21519519 | 0.80 | KMT2A (0.67) | KMT2AMAPTRAB9APOLBJMJD6 | |
| SCHEMBL21519616 | 0.80 | MAPT (0.53) | KMT2AMAPTRAB9APOLBKDM4E | |
| SCHEMBL21519620 | 0.80 | MAPT (0.53) | KMT2AMAPTRAB9APOLBKDM4E | |
| SCHEMBL21519372 | 0.80 | KMT2A (0.46) | KMT2AMAPTRAB9APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12006294-B2 | Therapeutic compounds | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2024-06-11 | — | — | US | disclosed |
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | REGENTS OF THE UNIVERSITY OF MINNESOTA | 2019-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190330157-A1 | THERAPEUTIC COMPOUNDS | OPRL1, INA, OGFR | KMT2A 3083/4885MAPT 3826/4885RAB9A 497/4885 |
| US-12006294-B2 | Therapeutic compounds | OPRL1, INA, OGFR | KMT2A 3083/4885MAPT 3826/4885RAB9A 497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.