Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.69 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | CA9 | Q16790 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 3/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mannitol SCHEMBL21522526 | 1.00 | LMNA (0.69) | LMNATSHRADRB2ADRB1ADRB3 | |
| Demannose SCHEMBL23521445 | 0.91 | LMNA (0.56) | LMNATSHRADRB2ADRB1ADRB3 | |
| Methyl Salicylate SCHEMBL27476177 | 0.87 | LMNA (0.73) | LMNATSHRADRB2ADRB1ADRB3 | |
| Methyl Salicylate SCHEMBL9561467 | 0.87 | LMNA (0.73) | LMNATSHRADRB2ADRB1ADRB3 | |
| Methyl Salicylate SCHEMBL4113789 | 0.83 | LMNA (0.85) | LMNATSHRTDP1NPC1KDM4E | |
| Methyl Salicylate SCHEMBL27571018 | 0.83 | LMNA (0.85) | LMNATSHRTDP1NPC1KDM4E | |
| Methyl Salicylate SCHEMBL28507609 | 0.83 | LMNA (0.85) | LMNATSHRADRB2ADRB1ADRB3 | |
| Methyl Salicylate SCHEMBL1872042 | 0.83 | LMNA (1.00) | LMNATSHRTDP1KDM4EGAA | |
| Methyl Salicylate SCHEMBL5312 | 0.83 | LMNA (1.00) | LMNATSHRTDP1KDM4EGAA | |
| Methyl Salicylate SCHEMBL29370254 | 0.83 | LMNA (1.00) | LMNATSHRTDP1KDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190328882-A1 | MICROBIOLOGICALLY SOUND AND STABLE SOLUTIONS OF GAMMA-HYDROXYBUTYRATE SALT FOR THE TREATMENT OF NARCOLEPSY | JAZZ PHARMACEUTICALS INC (US) | 2019-10-31 | — | — | US | disclosed |