SCHEMBL21522985

SCHEMBL21522985

CC(=O)OCNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.57
EPHX2 P34913 1/20 0.52
CASP3 P42574 3/20 0.49
FABP5 Q01469 3/20 0.45
FABP7 O15540 2/20 0.45
POLB P06746 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30001711 0.91 KMT2A (0.53) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL17003708 0.91 KMT2A (0.53) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL27333025 0.90 KMT2A (0.52) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL30877996 0.90 KMT2A (0.52) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL26518049 0.87 KMT2A (0.53) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL12665923 0.86 KMT2A (0.62) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL23882966 0.85 CASP3 (0.50) KMT2AEPHX2CASP3
SCHEMBL30001661 0.85 CASP3 (0.50) KMT2AEPHX2CASP3
SCHEMBL23882965 0.85 CASP3 (0.50) KMT2AEPHX2CASP3
SCHEMBL27443207 0.85 KMT2A (0.49) KMT2AEPHX2CASP3FABP5FABP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026099897-A1 NOVEL LINKERS AND ITS PREPARATION METHODS THEREOF ZYDUS LIFESCIENCES LIMITED (IN) 2026-05-15 WO disclosed
US-11845934-B2 Specific synthetic chimeric xenonucleic acid guide RNA; s(XNA-gRNA) for enhancing CRISPR mediated genome editing efficiency DiaCarta Inc. (US) 2023-12-19 US disclosed
US-20230295077-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE SIDE CHAIN FRESENIUS KABI ONCOLOGY LIMITED (IN) 2023-09-21 US disclosed
US-20220025453-A1 XENONUCLEIC ACID-MEDIATED MULTIPLEX QPCR CLAMPING TECHNOLOGY FOR LUNG CANCER MUTATION DETECTION Sha michael y (US) 2022-01-27 US disclosed
US-20220025437-A1 NOVEL METHOD OF COMBINED MOLECULAR CLAMPING AND ALLELE SPECIFIC qPCR TECHNOLOGY FOR KRAS G12C MUTATION DETECTION SUN QING (US) 2022-01-27 US disclosed
US-20220025453-A1 XENONUCLEIC ACID-MEDIATED MULTIPLEX QPCR CLAMPING TECHNOLOGY FOR LUNG CANCER MUTATION DETECTION Sha michael y (US) 2022-01-27 US disclosed
US-11208689-B2 DNA mutation detection employing enrichment of mutant polynucleotide sequences and minimally invasive sampling DIACARTA LTD 2021-12-28 US disclosed
US-11208689-B2 DNA mutation detection employing enrichment of mutant polynucleotide sequences and minimally invasive sampling DIACARTA LTD 2021-12-28 US disclosed
US-20190330692-A1 DNA MUTATION DETECTION EMPLOYING ENRICHMENT OF MUTANT POLYNUCLEOTIDE SEQUENCES AND MINIMALLY INVASIVE SAMPLING POWELL MICHAEL J (US) 2019-10-31 US disclosed
US-20190330621-A1 SPECIFIC SYNTHETIC CHIMERIC XENONUCLEIC ACID GUIDE RNA; s(XNA-gRNA) FOR ENHANCING CRISPR MEDIATED GENOME EDITING EFFICIENCY POWELL MICHAEL J (US) 2019-10-31 US disclosed
US-20190330692-A1 DNA MUTATION DETECTION EMPLOYING ENRICHMENT OF MUTANT POLYNUCLEOTIDE SEQUENCES AND MINIMALLY INVASIVE SAMPLING POWELL MICHAEL J (US) 2019-10-31 US disclosed
US-20190330621-A1 SPECIFIC SYNTHETIC CHIMERIC XENONUCLEIC ACID GUIDE RNA; s(XNA-gRNA) FOR ENHANCING CRISPR MEDIATED GENOME EDITING EFFICIENCY POWELL MICHAEL J (US) 2019-10-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190330621-A1 SPECIFIC SYNTHETIC CHIMERIC XENONUCLEIC ACID GUIDE RNA; s(XNA-gRNA) FOR ENHANCING CRISPR MEDIATED GENOME EDITING EFFICIENCY XPA, CDA, GDA KMT2A 331/4885EPHX2 3693/4885CASP3 2531/4885
US-11845934-B2 Specific synthetic chimeric xenonucleic acid guide RNA; s(XNA-gRNA) for enhancing CRISPR mediated genome editing efficiency XPA, CDA, GDA KMT2A 331/4885EPHX2 3693/4885CASP3 2531/4885
US-20230295077-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF SEMAGLUTIDE SIDE CHAIN GLP1R, GCG, GCGR KMT2A 3435/4885EPHX2 1604/4885CASP3 2947/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.