SCHEMBL17003708

SCHEMBL17003708

CC(=O)OCNC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.66

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.53
EPHX2 P34913 1/20 0.47
CASP3 P42574 3/20 0.45
OPRD1 P41143 1/20 0.43
CXCR2 P25025 1/20 0.41
FABP5 Q01469 2/20 0.41
FABP7 O15540 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30001711 1.00 KMT2A (0.53) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL27333025 0.99 KMT2A (0.52) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL30877996 0.99 KMT2A (0.52) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL21522985 0.91 KMT2A (0.57) KMT2AEPHX2CASP3FABP5FABP7
SCHEMBL20628606 0.90 KMT2A (0.51) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL20603546 0.89 KMT2A (0.50) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL21689327 0.87 KMT2A (0.55) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL29776526 0.86 KMT2A (0.52) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL16485219 0.86 KMT2A (0.52) KMT2AEPHX2CASP3OPRD1CXCR2
SCHEMBL29061468 0.86 KMT2A (0.47) KMT2AEPHX2CASP3OPRD1CXCR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4714956-A2 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE Daiichi Sankyo Company, Limited (JP) 2026-03-25 EP disclosed
US-12503489-B2 Method for producing antibody-drug conjugate DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-12-23 US disclosed
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
EP-3677589-B1 IMPROVED METHOD FOR PRODUCING ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO CO LTD (JP) 2025-11-26 EP disclosed
US-20250257146-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-08-14 US disclosed
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates DAIICHI SANKYO COMPANY, LIMITED (JP) 2025-07-29 US disclosed
EP-4538372-A2 ANTI-TROP2 ANTIBODY Daiichi Sankyo Company, Limited (JP) 2025-04-16 EP disclosed
EP-3424955-B1 METHOD FOR PRODUCING AN ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO CO LTD (JP) 2025-04-09 EP disclosed
EP-4524154-A2 ANTIBODY-DRUG CONJUGATES OF CYCLIC DINUCLEOTIDE DERIVATIVES Daiichi Sankyo Company, Limited (JP) 2025-03-19 EP disclosed
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. 2025-02-27 US disclosed
EP-3088419-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-11-02 EP disclosed
US-20160297890-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-10-13 US disclosed
US-20160297890-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-10-13 US disclosed
US-20160279259-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-09-29 US disclosed
US-20160279259-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2016-09-29 US disclosed
US-20150297748-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-10-22 US disclosed
US-20150297748-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-10-22 US disclosed
WO-2015155998-A1 ANTI-HER3 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-10-15 WO disclosed
WO-2015155998-A1 ANTI-HER3 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-10-15 WO disclosed
EP-2907824-A1 ANTIBODY-DRUG CONJUGATE DAIICHI SANKYO COMPANY, LIMITED (JP) 2015-08-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12370263-B2 Cyclic dinucleotide derivative based antibody-drug conjugates STING1, CGAS, CDA KMT2A 2775/4885EPHX2 1647/4885CASP3 2484/4885
US-20250257146-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE TAGLN2, TNNT2, TPM4 KMT2A 1096/4885EPHX2 2212/4885CASP3 3103/4885
US-20250064954-A1 STEROIDS AND ANTIBODY-CONJUGATES THEREOF SERPINA6, NR3C1, NR3C2 KMT2A 4385/4885EPHX2 2214/4885CASP3 4527/4885
US-12503489-B2 Method for producing antibody-drug conjugate UGT1A9, ALB, MRPL21 KMT2A 2459/4885EPHX2 968/4885CASP3 2801/4885
US-20160279259-A1 ANTIBODY-DRUG CONJUGATE LANCL2, LANCL1, LCLAT1 KMT2A 588/4885EPHX2 2444/4885CASP3 2168/4885
US-12497460-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR KMT2A 710/4885EPHX2 4662/4885CASP3 3644/4885
US-20150297748-A1 ANTIBODY-DRUG CONJUGATE LANCL2, LANCL1, LCLAT1 KMT2A 588/4885EPHX2 2444/4885CASP3 2168/4885
US-20160297890-A1 ANTI-TROP2 ANTIBODY-DRUG CONJUGATE TAGLN2, TNNT2, TPM4 KMT2A 1096/4885EPHX2 2212/4885CASP3 3103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.