SCHEMBL2152304

SCHEMBL2152304

COc1cccc(-c2nccs2)c1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.54
MGAM O43451 1/20 0.54
SI P14410 1/20 0.54
MGAM2 Q2M2H8 1/20 0.54
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
HSD17B10 Q99714 2/20 0.49
HPGD P15428 1/20 0.49
CTSA P10619 1/20 0.47
SMPD3 Q9NY59 1/20 0.46
TUBB4A P04350 4/20 0.44
TUBB P07437 4/20 0.44
TUBA3C P0DPH7 4/20 0.44
TUBA1B P68363 4/20 0.44
TUBA4A P68366 4/20 0.44
TUBB4B P68371 4/20 0.44
TUBB3 Q13509 4/20 0.44
TUBB2A Q13885 4/20 0.44
TUBB8 Q3ZCM7 4/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5396495 0.85 ADRA1D (0.52) ALDH1A1KDM4EHSD17B10HPGDCTSA
SCHEMBL29715238 0.85 ADRA1D (0.52) ALDH1A1KDM4EHSD17B10HPGDCTSA
SCHEMBL17198695 0.84 CTSA (0.47) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL20092688 0.83 MGAM (0.42) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL3201976 0.81 CTSA (0.45) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL18415038 0.80 TUBB4A (0.40) GAAALDH1A1KDM4ETDP1HSD17B10
SCHEMBL18415036 0.80 TYK2 (0.39) GAAMGAMSIMGAM2CTSA
SCHEMBL18415039 0.80 TUBB4A (0.40) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL23108267 0.79 CA1 (0.46) GAAALDH1A1KDM4ETDP1HPGD
SCHEMBL3201989 0.79 CTSA (0.45) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1722272-B1 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORP (JP) 2011-07-06 EP disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-20060257783-A1 Polymerizable composition and lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. 2006-11-16 US disclosed
EP-1722272-A1 Polymerizable composition and lithographic printing plate precursor Fuji Photo Film Co., Ltd. (JP) 2006-11-15 EP disclosed
EP-0385496-A2 Color light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1990-09-05 EP disclosed
EP-0377463-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-07-11 EP disclosed
EP-0005652-A2 Electrophoretic migration imaging process and dispersion EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1979-11-28 EP disclosed