Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | PTGFR | P43088 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19633875 | 0.86 | KCNK3 (0.38) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL22791876 | 0.84 | MPL (0.38) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL19506515 | 0.84 | TSHR (0.48) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL9061789 | 0.82 | PDE2A (0.40) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL1727979 | 0.82 | ALDH1A1 (0.39) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL12261514 | 0.82 | ALDH1A1 (0.39) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL1727859 | 0.82 | ALDH1A1 (0.39) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL16563567 | 0.81 | ALDH1A1 (0.38) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL19505951 | 0.80 | DHFR (0.37) | KCNK3KCNK9SLC6A2SLC6A4CYP2D6 | |
| SCHEMBL27644273 | 0.80 | GRIK1 (0.40) | KCNK3KCNK9PDE2APPARGL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | NAVITOR PHARMACEUTICALS, INC. (US) | 2020-11-24 | — | — | US | disclosed |
| US-10457703-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2019-10-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10844013-B2 | Phenyl amino piperidine mTORC inhibitors and uses thereof | MTOR, RICTOR, RPTOR | KCNK3 3577/4885KCNK9 4094/4885SLC6A2 3251/4885 |
| US-10457703-B2 | Bile acid derivatives as FXR/TGR5 agonists and methods of use thereof | GPBAR1, NR1H4, SLC10A1 | KCNK3 2902/4885KCNK9 3049/4885SLC6A2 1056/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.