Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | EP300 | Q09472 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16521581 | 0.86 | KDM4E (0.48) | KDM4EATML3MBTL1ALDH1A1ALOX15 | |
| SCHEMBL18214486 | 0.83 | KDM4E (0.54) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL28446443 | 0.81 | KDM4E (0.52) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL16848488 | 0.80 | HTR6 (0.44) | KDM4EL3MBTL1ALDH1A1HSD17B10MEN1 | |
| SCHEMBL29267945 | 0.79 | KDM4E (0.48) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL31403836 | 0.77 | KDM4E (0.47) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL14039112 | 0.77 | KDM4E (0.37) | KDM4EATML3MBTL1ALDH1A1MEN1 | |
| SCHEMBL24777362 | 0.76 | KDM4E (0.50) | KDM4EATML3MBTL1ALDH1A1HSD17B10 | |
| SCHEMBL14039079 | 0.76 | KDM4E (0.36) | KDM4EATML3MBTL1MEN1KMT2A | |
| SCHEMBL12811692 | 0.76 | KDM4E (0.36) | KDM4EATML3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10461269-B2 | Crosslinkable, /polymerizable and combinations thereof charge-transporting molecular glass mixtures, luminescent molecular glass mixtures, or combinations thereof for organic light emitting diodes and other organic electronics and photonics applications and method of making same | MOLECULAR GLASSES, INC. (US) | 2019-10-29 | — | — | US | disclosed |