Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | GPR3 | P46089 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28446443 | 0.86 | KDM4E (0.52) | KDM4EATML3MBTL1IDO1POLB | |
| SCHEMBL29267945 | 0.83 | KDM4E (0.48) | KDM4EATML3MBTL1IDO1POLB | |
| SCHEMBL29267935 | 0.83 | KDM4E (0.48) | KDM4EATML3MBTL1POLBKMT2A | |
| SCHEMBL16521581 | 0.83 | KDM4E (0.48) | KDM4EATML3MBTL1IDO1POLB | |
| SCHEMBL21524840 | 0.83 | KDM4E (0.48) | KDM4EATML3MBTL1IDO1POLB | |
| SCHEMBL31403836 | 0.82 | KDM4E (0.47) | KDM4EATML3MBTL1IDO1POLB | |
| SCHEMBL24777362 | 0.80 | KDM4E (0.50) | KDM4EATML3MBTL1POLBALOX5 | |
| SCHEMBL24513159 | 0.78 | KDM4E (0.43) | KDM4EATML3MBTL1POLBKMT2A | |
| SCHEMBL77361 | 0.78 | L3MBTL1 (0.84) | KDM4EATML3MBTL1POLBKMT2A | |
| SCHEMBL31397606 | 0.78 | L3MBTL1 (0.84) | KDM4EATML3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2018-05-17 | — | — | US | disclosed |
| WO-2016178827-A1 | FOUR-COORDINATE BORON COMPOUNDS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180138407-A1 | FOUR-COORDINATE BORON COMPOUNDS | C5, RBBP5, C2CD5 | KDM4E 1077/4885ATM 2616/4885L3MBTL1 401/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.