Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.45 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13017774 | 1.00 | MEN1 (0.45) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL21819723 | 1.00 | MEN1 (0.45) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL13427455 | 0.95 | MEN1 (0.49) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL15478190 | 0.92 | PPARA (0.48) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL9908065 | 0.91 | MEN1 (0.45) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8804349 | 0.88 | MEN1 (0.44) | MEN1KMT2AHRH3PPARAPPARG | |
| SCHEMBL15249766 | 0.85 | LTA4H (0.53) | MEN1MAPK1KMT2AHRH3PPARA | |
| SCHEMBL5188564 | 0.84 | LMNA (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL5188570 | 0.84 | LMNA (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL19996603 | 0.84 | LMNA (0.60) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3563185-B1 | POLARIZING ARTICLE AND METHOD OF FORMING A POLARIZING ARTICLE | TRANSITIONS OPTICAL LTD (IE) | 2024-01-31 | — | — | EP | disclosed |
| CN-110114703-B | Polarized article and method of forming a polarized article | 光学转变有限公司 | 2022-01-11 | — | — | CN | disclosed |
| US-10884288-B2 | Polarizing article and method of forming a polarizing article | TRANSITIONS OPTICAL, LTD. (IE) | 2021-01-05 | — | — | US | disclosed |
| US-20200103571-A1 | Polarizing Article and Method of Forming a Polarizing Article | TRANSITIONS OPTICAL, LTD. (IE) | 2020-04-02 | — | — | US | disclosed |
| EP-3563185-A1 | POLARIZING ARTICLE AND METHOD OF FORMING A POLARIZING ARTICLE | Transitions Optical, Ltd. (IE) | 2019-11-06 | — | — | EP | disclosed |