Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.76 |
| ▸ | TUBB1 | Q9H4B7 | 11/20 | 0.67 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.67 |
| ▸ | TUBB | P07437 | 7/20 | 0.67 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.67 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.67 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.67 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.67 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.67 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.67 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.67 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.67 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.67 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.67 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.67 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.67 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.62 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.62 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.59 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Naphthylcombretastatin SCHEMBL20332774 | 1.00 | NQO2 (0.76) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| Naphthylcombretastatin SCHEMBL20332776 | 1.00 | NQO2 (0.76) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5686445 | 0.83 | TUBB1 (0.67) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5686498 | 0.83 | TUBB1 (0.67) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL5686446 | 0.83 | TUBB1 (0.67) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6896671 | 0.82 | TUBB1 (0.85) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL631213 | 0.82 | TUBB1 (0.85) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL4659251 | 0.82 | TUBB1 (0.85) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL9184995 | 0.80 | TUBB1 (1.00) | NQO2TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL4416013 | 0.80 | TUBB1 (1.00) | NQO2TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-03-30 | — | — | US | disclosed |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-09-06 | — | — | US | disclosed |
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2019-11-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190337880-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS-AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | NQO2 2619/4885TUBB1 1736/4885TUBB4A 1190/4885 |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | SOX18, PROX1, RUNX1 | NQO2 2619/4885TUBB1 1736/4885TUBB4A 1190/4885 |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | NQO2 2533/4885TUBB1 1896/4885TUBB4A 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.