Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 9/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 7/20 | 1.00 |
| ▸ | TUBB | P07437 | 7/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 7/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 7/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 7/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 7/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 7/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 1.00 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 1.00 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 1.00 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.68 |
| ▸ | NQO2 | P16083 | 1/20 | 0.68 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.67 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919833 | 1.00 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL9184995 | 1.00 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Dimethylamine SCHEMBL9187869 | 0.94 | TUBB1 (0.89) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2622577 | 0.92 | TUBB1 (0.86) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL12651885 | 0.90 | TUBB1 (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6896671 | 0.90 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL631213 | 0.90 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4659251 | 0.90 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Sulfamate SCHEMBL21980869 | 0.88 | TUBB1 (0.78) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Sulfamate SCHEMBL21980858 | 0.88 | TUBB1 (0.78) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1826330-A | Combretastatin derivatives with cytotoxic action | SIGMA TAU IND FARMACEUTI (IT) | 2006-08-30 | — | — | CN | claimed |
| EP-1003033-A1 | Sensor comprising an oligomer binding layer and method of making such sensor and arrays of such sensors | INTERUNIVERSITAIR MICRO-ELEKTRONICA CENTRUM VZW (BE) | 2000-05-24 | — | — | EP | claimed |
| US-12410116-B2 | Compounds and use thereof in methods of treatment | THE UNIVERSITY OF QUEENSLAND (AU) | 2025-09-09 | — | — | US | disclosed |
| US-12404221-B2 | Methods of arene alkenylation | UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) | 2025-09-02 | — | — | US | disclosed |
| US-20240002326-A1 | COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT | THE UNIVERSITY OF QUEENSLAND (AU) | 2024-01-04 | — | — | US | disclosed |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-07-27 | — | — | US | disclosed |
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | UNIVERSITY OF VIRGINIA PATENT FOUNDATION | 2023-07-27 | — | — | US | disclosed |
| EP-2810198-B1 | ANTI-INVASIVE COMPOUNDS | UNIV GENT (BE) | 2023-07-12 | — | — | EP | disclosed |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | THE UNIVERSITY OF QUEENSLAND (AU) | 2023-03-30 | — | — | US | disclosed |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | THE UNIVERSITY OF QUEENSLAND (AU) | 2022-09-06 | — | — | US | disclosed |
| CN-212017750-U | 3, 5-dihydroxy benzoic acid methylation reaction device | 江苏惠利生物科技有限公司 | 2020-11-27 | — | — | CN | disclosed |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | UNIVERSITEIT GENT (BE) | 2015-01-08 | — | — | US | disclosed |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | STC.UNM (US) | 2013-07-11 | — | — | US | disclosed |
| EP-1668417-B1 | PHOTOPOLYMERIZABLE COMPOSITION. | AGFA GRAPHICS NV (BE) | 2009-05-13 | — | — | EP | disclosed |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | REGENTS OF THE UNIVERSITY OF NEW MEXICO | 2007-10-25 | — | — | US | disclosed |
| EP-1003033-A1 | Sensor comprising an oligomer binding layer and method of making such sensor and arrays of such sensors | INTERUNIVERSITAIR MICRO-ELEKTRONICA CENTRUM VZW (BE) | 2000-05-24 | — | — | EP | disclosed |
| EP-1003032-A1 | Sensor comprising an oligomer binding layer and method of making such sensor and arrays of such sensors | INTERUNIVERSITAIR MICRO-ELEKTRONICA CENTRUM VZW (BE) | 2000-05-24 | — | — | EP | disclosed |
| EP-0041043-B1 | PROCESS FOR THE PREPARATION OF DERIVATIVES OF ALKENYL BENZENE OR ALKENYL NAPHTHALENE | CIBA-GEIGY AG (CH) | 1983-11-09 | — | — | EP | disclosed |
| US-4335055-A | Process for the preparation of alkenylbenzene derivatives or alkenylnaphthalene derivatives | CIBA-GEIGY CORPORATION (US) | 1982-06-15 | — | — | US | disclosed |
| EP-0041043-A1 | Process for the preparation of derivatives of alkenyl benzene or alkenyl naphthalene | CIBA-GEIGY AG (CH) | 1981-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234900-A1 | METHODS OF ARENE ALKENYLATION | CYBB, CBR3, AHR | TUBB1 2622/4885TUBB4A 2530/4885TUBB 1774/4885 |
| US-11434190-B2 | Inhibitors of SOX18 protein activity for treating angiogenesis-and/or lymphangiogenesis-related diseases | SOX18, PROX1, RUNX1 | TUBB1 1736/4885TUBB4A 1190/4885TUBB 1697/4885 |
| US-20230100768-A1 | INHIBITORS OF SOX18 PROTEIN ACTIVITY FOR TREATING ANGIOGENESIS AND/OR LYMPHANGIOGENESIS-RELATED DISEASES | SOX18, PROX1, RUNX1 | TUBB1 1896/4885TUBB4A 1240/4885TUBB 1858/4885 |
| US-20070249647-A1 | Substituted CIS- and trans-stilbenes as therapeutic agents | TGFB1, VHL, TMSB10 | TUBB1 33/4885TUBB4A 144/4885TUBB 58/4885 |
| US-12404221-B2 | Methods of arene alkenylation | CYBB, CBR3, AHR | TUBB1 2622/4885TUBB4A 2530/4885TUBB 1774/4885 |
| US-20150011620-A1 | ANTI-INVASIVE COMPOUNDS | MMP3, MMP10, MIF | TUBB1 548/4885TUBB4A 776/4885TUBB 943/4885 |
| US-20130178536-A1 | SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS | PSEN1, TERT, PSEN2 | TUBB1 120/4885TUBB4A 271/4885TUBB 196/4885 |
| US-12410116-B2 | Compounds and use thereof in methods of treatment | SOX18, PROX1, RUNX1 | TUBB1 221/4885TUBB4A 126/4885TUBB 198/4885 |
| US-20240002326-A1 | COMPOUNDS AND USE THEREOF IN METHODS OF TREATMENT | SOX18, PROX1, RUNX1 | TUBB1 221/4885TUBB4A 126/4885TUBB 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.