Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Dodecanoate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.50 |
| ▸ | PPARG | P37231 | 7/20 | 0.50 |
| ▸ | PPARD | Q03181 | 7/20 | 0.50 |
| ▸ | PPARA | Q07869 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.50 |
| ▸ | FABP4 | P15090 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TLR2 | O60603 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Myristic Acid SCHEMBL3249423 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL6841075 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL3249425 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL3245114 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL8774854 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL3252157 | 0.89 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL28545595 | 0.84 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 | |
| Glycinebetaine SCHEMBL2046692 | 0.84 | TSHR (0.46) | TSHRALDH1A1TDP1ALOX15APP | |
| Glycinebetaine SCHEMBL20183465 | 0.82 | MAPT (0.46) | TSHRKMT2AHSD17B10MEN1MAPT | |
| Oleic Acid SCHEMBL3250070 | 0.81 | PPARG (0.70) | PPARGPPARDPPARATSHRPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519587-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | Dow Corning Toray Co., Ltd. (JP) | 2012-11-07 | — | — | EP | disclosed |
| WO-2011081218-A1 | PHENYL-CONTAINING ORGANOPOLYSILOXANE COMPOSITION, RAW COSMETIC MATERIAL, AND GLOSSY COSMETIC MATERIAL | DOW CORNING TORAY CO., LTD. (JP) | 2011-07-07 | — | — | WO | disclosed |