Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Palmitic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.63 |
| ▸ | PPARG | P37231 | 7/20 | 0.63 |
| ▸ | PPARD | Q03181 | 7/20 | 0.63 |
| ▸ | PPARA | Q07869 | 7/20 | 0.63 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.63 |
| ▸ | TSHR | P16473 | 4/20 | 0.63 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.63 |
| ▸ | FABP4 | P15090 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | TLR2 | O60603 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.63 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 1/20 | 0.63 |
| ▸ | PDE4A | P27815 | 1/20 | 0.63 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL3249425 | 1.00 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Myristic Acid SCHEMBL3249423 | 1.00 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL6841075 | 1.00 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL8774854 | 1.00 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL3245114 | 1.00 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Oleic Acid SCHEMBL3250070 | 0.91 | PPARG (0.70) | PPARGPPARDPPARATSHRPTPN1 | |
| Adipic Acid SCHEMBL5474223 | 0.90 | TSHR (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL2153140 | 0.89 | GPR84 (0.50) | GPR84PPARGPPARDPPARAHDAC11 | |
| Linoleic Acid SCHEMBL6907651 | 0.87 | PPARG (0.72) | PPARGPPARDPPARATSHRPTPN1 | |
| Glycinebetaine SCHEMBL9452080 | 0.84 | FFAR3 (0.56) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1475080-B1 | Cosmetic composition for the treatment of skin ageing and/or stressed skin | KUHS GMBH (DE) | 2018-04-04 | — | — | EP | claimed |
| EP-1259218-B1 | COSMETIC COMPOSITION FOR THE TREATMENT OF SKIN AGEING AND/OR STRESSED SKIN | KUHS GMBH (DE) | 2010-05-26 | — | — | EP | claimed |
| US-7192597-B2 | Composition for treatment of skin, hair and nails | KUHS GMBH (DE) | 2007-03-20 | — | — | US | claimed |
| US-7001604-B2 | Cosmetic composition | KUBS KOSMETIK GMBH & CO. KG (DE) | 2006-02-21 | — | — | US | claimed |
| EP-1411781-B1 | ADDITIVE FOR USE IN FEEDING STUFF OR DRINKING WATER | BERG & SCHMIDT GMBH & CO (DE) | 2006-01-25 | — | — | EP | claimed |
| US-20050208012-A1 | Composition for treatment of skin, hair and nails | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2005-09-22 | — | — | US | claimed |
| US-20040235783-A1 | Pharmaceutical compositions for the treatment of tumor diseases | GHYCZY MIKLOS (DE) | 2004-11-25 | — | — | US | claimed |
| US-20010021704-A1 | Pharmaceutical compositions for the treatment of tumor diseases | RHONE-POULENC RORER GMBH, KOLN (DE) | 2001-09-13 | — | — | US | claimed |
| EP-1992322-A1 | Composition for percutaneous application | Dr. Scheller Cosmetics AG (DE) | 2008-11-19 | — | — | EP | disclosed |
| WO-2008057423-A1 | KITS CONTAINING BENZOYL PEROXIDE PADS AND A BARRIER REPAIR COMPOSITION, AND FORMULATIONS AND METHODS OF USE THEREFOR | STIEFEL LABORATORIES, INC. (US) | 2008-05-15 | — | — | WO | disclosed |
| US-7192597-B2 | Composition for treatment of skin, hair and nails | KUHS GMBH (DE) | 2007-03-20 | — | — | US | disclosed |
| US-7001604-B2 | Cosmetic composition | KUBS KOSMETIK GMBH & CO. KG (DE) | 2006-02-21 | — | — | US | disclosed |
| US-20050208012-A1 | Composition for treatment of skin, hair and nails | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2005-09-22 | — | — | US | disclosed |
| US-20040235783-A1 | Pharmaceutical compositions for the treatment of tumor diseases | GHYCZY MIKLOS (DE) | 2004-11-25 | — | — | US | disclosed |
| US-20040213819-A1 | Cosmetic composition | LG HOUSEHOLD & HEALTH CARE LTD. (KR) | 2004-10-28 | — | — | US | disclosed |
| US-20010021704-A1 | Pharmaceutical compositions for the treatment of tumor diseases | RHONE-POULENC RORER GMBH, KOLN (DE) | 2001-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040235783-A1 | Pharmaceutical compositions for the treatment of tumor diseases | GLS, HOGA1, NDUFB5 | GPR84 3458/4885PPARG 347/4885PPARD 611/4885 |
| US-20010021704-A1 | Pharmaceutical compositions for the treatment of tumor diseases | GLS, HOGA1, NDUFB5 | GPR84 3458/4885PPARG 347/4885PPARD 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.